research LHX2 Is a Direct NF-κB Target Gene That Promotes Primary Hair Follicle Placode Down-Growth
LHX2 is essential for hair follicle development, controlled by NF-κB and TGFβ2 signaling.
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research TGF-β2 Is Specifically Expressed in Human Dermal Papilla Cells and Modulates Hair Folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
research 5α-Reductase Activity in the Human Hair Follicle Concentrates in the Dermal Papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics
Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
research Skin Permeation of Different Steroid Hormones from Polymeric Coated Liposomal Formulations
Polymers increased skin permeation and stability of steroid hormones in liposomal formulations.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research The Dynamic Duo: Niche and Stem Cell Interdependency
Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.
research Wound Healing in Development: Mechanisms and Regulation
Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
research Hedgehog Signaling Reprograms Hair Follicle Niche Fibroblasts to a Hyper-Activated State
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
research Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane-Induced Dystrophy and Redirect Polyunsaturated Fatty Acid Metabolism Toward β-Oxidation
Annurca apple extract may protect mouse hair from damage by chemotherapy and could help treat hair loss without promoting cancer growth.
research Defining the Localization and Molecular Characteristics of Minor Salivary Gland Label-Retaining Cells
The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
research Small RNAs Loom Large During Reprogramming
MicroRNAs can reprogram cells into stem cells faster and more efficiently than traditional methods.
research Generation of Tβ4 Knock-In Cashmere Goat Using CRISPR/Cas9
Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.
research Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition
Researchers found a genetic region that influences the number of coat layers in dogs.
research Cartilage Oligomeric Matrix Protein Forms Part of the Connective Tissue of Normal Human Hair Follicles
A protein called COMP is part of the connective tissue in normal human hair follicles and may be important for hair health.
research Let-7b Promotes Alpaca Hair Growth via Transcriptional Repression of TGFβR I
Let-7b helps alpaca hair grow by reducing TGFβR I protein.
research Interferon Beta Secreted from Human Hair Dermal Papilla Cells Inhibits the Growth of Outer Root Sheath Cells Cultured in Vitro
Interferon β from hair cells stops the growth of other hair cells.
research Live Imaging of Smad2/3 Signaling in Mouse Skin Wound Healing
Smad2/3-dependent TGF-β signaling increases during wound healing.
research Reduced SMAD2/3 Activation Independently Predicts Increased Depth of Human Cutaneous Squamous Cell Carcinoma
Lower SMAD2/3 activation predicts more severe skin cancer.
research Hairless Up-Regulates TGF-β2 Expression via Down-Regulation of miR-31 in the Skin of Hairpoor (HrHp) Mice
HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.
research Therapeutic Effect of Mesenchymal Stem Cells on Histopathological, Immunohistochemical, and Molecular Analysis in Second-Degree Burn Model
Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.
research All-Trans-Retinoic Acid Inhibits Mink Hair Follicle Growth by Inhibiting Proliferation and Inducing Apoptosis of Dermal Papilla Cells Through TGF-β2/Smad2/3 Pathway
All-trans-retinoic acid stops mink hair growth by affecting cell growth and causing cell death.
research TGFβ Family Mimetic Peptide Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice
A peptide called DPS-1 helps human scalp cells grow and stimulates hair growth in mice.
research The Epithelial Stem Cell Niche in Skin
Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
research Identification of Key Genes and Signaling Pathways Related to Hetian Sheep Wool Density by RNA-Seq Technology
Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.
research QR678 and QR678 Neo Hair Growth Formulations: A Cellular Toxicity and Animal Efficacy Study
QR 678 and QR 678 Neo are safe and promote hair growth, potentially helping chemotherapy-induced hair loss.
research Chondrogenic Differentiation of Human Scalp Adipose-Derived Stem Cells in Polycaprolactone Scaffold Using Freeze Thaw Freeze Method
Human scalp fat stem cells showed improved cartilage-like development on a special scaffold with freeze-thaw treatment.
research Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors by Microarray Analysis
Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
research Mimicking Hair Disorders by Genetic Manipulation of Organ-Cultured Human Hair Follicles
Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.
research From Hair to Liver: Emerging Application of Hair Follicle Mesenchymal Stem Cell Transplantation Reverses Liver Cirrhosis by Blocking the TGF-β/Smad Signaling Pathway to Inhibit Pathological HSC Activation
Hair follicle stem cell transplants can reverse liver cirrhosis by blocking harmful cell activation.