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Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Minoxidil can reduce functions related to androgen receptors.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Skin organoids are a promising new model for studying human skin development and testing treatments.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.

Cannabinoids might help treat skin problems but more research is needed to be sure.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

New regenerative therapies show promise for treating hair loss.

Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Nanomaterials can significantly improve wound healing and future treatments may include smart, real-time monitoring.

Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.

Synthetic ceramides may help hair growth by boosting cell growth in hair follicles.

Researchers made a cell line that grows quickly and can help with hair growth research.

Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.

Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.

Asiasari radix extract may be a potential treatment for melanoma because it selectively triggers cell death in melanoma cells by affecting p53 regulation.

Platycladus orientalis leaf extract helps hair grow by activating certain proteins.

Targeting specific miRNAs may help treat hair follicle issues caused by hydrogen peroxide.

Houttuynia cordata extract may help hair grow by improving cell survival and increasing cell growth.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Human placental extract may help hair growth by affecting certain cell signals and could be more effective with minoxidil.