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Chromosomal differences affect how muscle cells respond to testosterone.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

TGFβ signaling prevents sebaceous gland cells from producing fats.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

The secretome from mesenchymal stromal cells shows promise for improving facial nerve injury treatment.

Fibroblast growth factors are crucial for hair follicle development and regeneration.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

Mutations in certain receptors can cause diseases and offer new treatment options.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

PCOS has many symptoms, with high androgen levels being the most common.

A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.

Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.

Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

Glioblastoma cells can make androgens, which might help the tumor grow.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.