Systematic Review on the Various Clinical Features of Polycystic Ovary Syndrome (PCOS) Patients

    March 2024 in “ International journal of life-sciences scientific research/SSR Institute of International Journal of Life Sciences ”
    Anjum Farhana, Jian Shi
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    TLDR PCOS has many symptoms, with high androgen levels being the most common.
    The systematic review of ten studies on PCOS highlights its multifaceted nature, with increased androgen levels being the most frequently observed feature in 70% of the studies. Hirsutism was prevalent in 60% of the studies, and metabolic implications such as increased waist-to-hip ratio and elevated lipid levels were reported in 50% of the studies. Serum testosterone levels and acne were significant in 30% of the studies. Metformin's effectiveness in restoring regular menstrual cycles was noted in 10% of the studies. Less frequently documented features included increased plasma estradiol levels, alopecia, and male pattern hair loss (20% of the studies), and acanthosis nigricans (30% of the studies). These findings underscore the importance of tailored management approaches to address the complex nature of PCOS effectively.
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      in Update  34 upvotes 6 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

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