TLDR To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.
The 2006 document details the diagnostic criteria for Polycystic Ovarian Syndrome (PCOS), based on the 2003 Rotterdam consensus, which requires the presence of at least two of the following three features for a diagnosis: oligomenorrhea or amenorrhea, clinical or biochemical hyperandrogenism, and polycystic ovaries on ultrasound. It highlights the association of PCOS with obesity, insulin resistance, and metabolic syndrome, which pose long-term health risks. The document also discusses the prevalence of hirsutism (approximately 60%), acne (one-third of cases), and male pattern hair loss in PCOS, which requires a familial predisposition. It emphasizes the need to exclude other conditions like congenital adrenal hyperplasia, Cushing's syndrome, and androgen-producing neoplasms that can mimic PCOS symptoms. The Rotterdam criteria are recommended for uniformity in research and clinical management, acknowledging the heterogeneity of PCOS symptoms and endocrine profiles, and the potential increase in PCOS prevalence to up to 10% among the general female population.
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278 citations
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October 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Polycystic ovaries are defined by having 12 or more small follicles in each ovary and are found in up to 33% of women, while Polycystic Ovary Syndrome (PCOS) is the most common hormone disorder in women of reproductive age, potentially increasing risk of obesity, diabetes, and heart diseases.
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January 2004 in “Fertility and Sterility” The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
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January 2004 in “Human Reproduction” The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
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January 2000 in “Hormone research in paediatrics” Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
216 citations
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November 1999 in “Fertility and Sterility” Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.
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September 1995 in “New England journal of medicine/The New England journal of medicine” PCOS is a common hormonal disorder causing irregular periods and increased hair growth, linked to insulin resistance and long-term health issues.
54 citations
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February 1993 in “Endocrine reviews” Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.