Polycystic Ovarian Syndrome in Taiwanese Women
October 2010
in “
Journal of Experimental & Clinical Medicine
”
Polycystic Ovary Syndrome PCOS Rotterdam criteria National Institutes of Health criteria hyperandrogenic chronic anovulation luteinizing hormone follicle-stimulating hormone insulin resistance impaired glucose tolerance type 2 diabetes obesity androgen excess metabolic syndrome NIH criteria LH FSH IGT T2D
TLDR Obesity is a major risk factor for insulin resistance in Taiwanese women with PCOS, which is also an independent risk factor for metabolic syndrome.
The document reports on Polycystic Ovary Syndrome (PCOS) in Taiwanese women, indicating that 61% of those diagnosed with PCOS using the Rotterdam criteria also met the National Institutes of Health criteria for hyperandrogenic chronic anovulation. Taiwanese women with PCOS typically have a higher luteinizing hormone to follicle-stimulating hormone ratio and lower insulin resistance than Western women, potentially due to a lower average body mass index. The prevalence of impaired glucose tolerance and type 2 diabetes among Chinese women with PCOS is significant, with studies showing a range of 7.6% to 31.1% for IGT and 1.0% to 16.6% for type 2 diabetes. Obesity, affecting 40-50% of PCOS patients, worsens symptoms and increases the risk of diabetes and cardiovascular issues. The document includes findings from studies with sample sizes of 1040, 102, 356, and 254 Chinese women with PCOS. It concludes that obesity is a more significant risk factor for insulin resistance in PCOS than other factors and that PCOS without androgen excess may be a milder form of the syndrome, while PCOS itself is an independent risk factor for metabolic syndrome.
