75 citations,
October 2012 in “Journal of Investigative Dermatology” Alopecia areata can be triggered by specific immune cells without genetic or environmental factors.
25 citations,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” A new mouse model helps understand and find treatments for alopecia areata.
April 2019 in “Journal of Investigative Dermatology” The humanized AA mouse model is better for testing new alopecia areata treatments.
42 citations,
March 2010 in “Endocrinology” Mice with human gene experienced hair loss when treated with DHT.
3 citations,
April 2010 in “Endocrinology” The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.
October 2023 in “Acta dermato-venereologica” Minoxidil and platelet-rich plasma can help turn thin hair into thicker hair in male pattern baldness.
29 citations,
November 2011 in “Cell stress & chaperones” Quercetin effectively treated and prevented hair loss in mice.
25 citations,
August 2014 in “Endocrinology” Researchers created a mouse model of a type of rickets that does not cause hair loss.
August 2021 in “Journal of Investigative Dermatology” Platelet-rich plasma (PRP) helps regrow hair in male pattern baldness.
1 citations,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.
North American ginseng extract helped regrow hair in balding mice.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
81 citations,
July 2011 in “Lasers in Medical Science” The Lexington LaserComb helped regrow hair in mice with a condition similar to human hair loss.
5 citations,
June 2019 in “British Journal of Dermatology” Tofacitinib was more effective than apremilast in treating hair loss in a mouse model of alopecia areata.
April 2024 in “Histochemistry and cell biology” N-acetylcysteine may prevent hair loss caused by chemotherapy.
August 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” TAGX-0003 protected hair follicles and reversed alopecia areata in a mouse model.
February 2020 in “Int J Biologicals” Super-activated platelet lysate significantly promotes hair regrowth in mice with androgenetic alopecia.
November 2022 in “Journal of Investigative Dermatology” Minoxidil and PRP can help convert miniaturized hair follicles back to normal in male pattern baldness.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” TYK2 inhibition may help treat alopecia areata by promoting hair growth and reducing immune response.
July 2022 in “Journal of Investigative Dermatology” Inhibiting TYK2 can restore hair growth in alopecia areata.
September 2016 in “Journal of the Society of Cosmetic Scientists of Korea” Pine resin and abietic acid were found to promote hair growth in mice.
3 citations,
December 2014 in “Daehan miyong hakoeji” 3 citations,
January 2016 in “Biotechnology and Bioprocess Engineering” Laminaria japonica extract with IGF-1 improved mouse hair growth and could be a potential alopecia treatment.
1 citations,
April 2024 in “Journal of Pharmaceutical and Pharmacological Sciences” The mouse models are effective for testing new hair loss treatments.
35 citations,
August 2010 in “The American journal of pathology” Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
1 citations,
September 2019 in “Journal of Investigative Dermatology” Anti-Desmocollin 3 antibodies can cause pemphigus-like symptoms in mice.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study developed a mouse model for Alopecia Areata that responds to treatment, useful for future research.
37 citations,
June 2000 in “Experimental dermatology” The Lanceolate hair-J mutation in mice mimics human hair disorders like Netherton's syndrome.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking JAK1 or JAK3 helps reverse hair loss in a mouse model of alopecia areata.