Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus

    September 2019 in “ Journal of Investigative Dermatology ”
    Roberta Lotti, Claudio Giacinto Atene, Alessandra Marconi … Carlo Pincelli
    Studysummary This study developed a pemphigus model in mice showing that anti-Desmocollin 3 and anti-Desmoglein 3 antibodies lead to more severe disease, suggesting diverse antigens contribute to varying human pemphigus phenotypes.
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