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GlossaryAcantholysis

breakdown of connections between skin cells causing separation

Acantholysis is a condition where the connections between skin cells break down, causing the cells to separate from each other. This leads to the formation of blisters and can be seen in diseases like pemphigus vulgaris. Essentially, it's a breakdown in the "glue" that holds skin cells together, resulting in fragile skin that can easily blister or peel.

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research Alopecia as a Rare but Distinct Manifestation of Pemphigus Vulgaris

23 citations, November 2011 in “Journal of the European Academy of Dermatology and Venereology”

Hair loss is a rare but recognized symptom of pemphigus vulgaris, with patients usually regrowing hair after treatment.

research Distinguishing Histopathologic Features of Acantholytic Dermatoses and the Pattern of Acantholytic Hypergranulosis

20 citations, September 2018 in “Journal of cutaneous pathology”

Different skin diseases show unique patterns of skin cell separation, cell death, and granular layer changes.

research Acantholytic Hair Casts: A Dermoscopic Sign of Pemphigus Vulgaris of the Scalp

15 citations, January 2012 in “International Journal of Trichology”

Hair casts on the scalp may be a sign of ongoing pemphigus vulgaris and could suggest a need to adjust treatment.

research Miniaturization of Sebaceous Glands: A Novel Histopathological Finding in Pemphigus Vulgaris and Pemphigus Foliaceus of the Scalp

9 citations, June 2017 in “Journal of Cutaneous Pathology”

People with pemphigus vulgaris and pemphigus foliaceus often have smaller sebaceous glands on their scalp.

research A Case of Pemphigus Vulgaris Developing After Platelet-Rich Plasma Treatment

1 citations, January 2020 in “Turk Dermatoloji Dergisi”

A woman developed a skin condition called Pemphigus Vulgaris after a treatment to help with hair loss.

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