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    Glossary Acantholysis

    breakdown of connections between skin cells causing separation

    Acantholysis is a condition where the connections between skin cells break down, causing the cells to separate from each other. This leads to the formation of blisters and can be seen in diseases like pemphigus vulgaris. Essentially, it's a breakdown in the "glue" that holds skin cells together, resulting in fragile skin that can easily blister or peel.

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    1. Distinguishing histopathologic features of acantholytic dermatoses and the pattern of acantholytic hypergranulosis Journal of cutaneous pathology · 2018 · 20 citations
    2. Acantholytic hair casts: A dermoscopic sign of pemphigus vulgaris of the scalp International Journal of Trichology · 2012 · 15 citations
    3. Acanthosis nigricans, insulin resistance and cutaneous virilism British Journal of Dermatology · 1988 · 43 citations
    4. Acanthosis nigricans and the metabolic syndrome Clinics in Dermatology · 2017 · 30 citations
    5. Insulin Resistance, Acanthosis Nigricans, and Polycystic Ovaries Associated with a Circulating Inhibitor of Postbinding Insulin Action The Journal of Clinical Endocrinology & Metabolism · 1985 · 24 citations
    6. Implications of a Clinically Ignored Site of Acanthosis Nigricans: The Knuckles Experimental and Clinical Endocrinology & Diabetes · 2014 · 9 citations
    7. Hyperandrogenism-Insulin Resistance-Acanthosis Nigricans Syndrome Case reports in endocrinology · 2015 · 7 citations
    8. Acanthosis nigricans in the knuckles: An early, accessible, straightforward, and sensitive clinical tool to predict insulin resistance Dermato-endocrinology · 2018 · 6 citations
    9. A case of hyperpigmentation and acanthosis nigricans by testosterone injections Human & experimental toxicology · 2014 · 6 citations
    10. Global hotspots and trends in Acanthosis nigricans research: A bibliometric and visualized analysis Skin Research and Technology · 2024 · 3 citations
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