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    Glossary Acanthosis

    thickening of skin's outer layer, often with dark patches

    Acanthosis refers to the thickening of the skin's outer layer, often characterized by dark, velvety patches, typically found in body folds like the neck, armpits, and groin. This condition is commonly associated with insulin resistance, obesity, and certain hormonal disorders, and can be a marker for underlying health issues such as type 2 diabetes.

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    1. Acanthosis nigricans, insulin resistance and cutaneous virilism British Journal of Dermatology · 1988 · 43 citations
    2. Acanthosis nigricans and the metabolic syndrome Clinics in Dermatology · 2017 · 30 citations
    3. Insulin Resistance, Acanthosis Nigricans, and Polycystic Ovaries Associated with a Circulating Inhibitor of Postbinding Insulin Action The Journal of Clinical Endocrinology & Metabolism · 1985 · 24 citations
    4. Implications of a Clinically Ignored Site of Acanthosis Nigricans: The Knuckles Experimental and Clinical Endocrinology & Diabetes · 2014 · 9 citations
    5. Hyperandrogenism-Insulin Resistance-Acanthosis Nigricans Syndrome Case reports in endocrinology · 2015 · 7 citations
    6. Acanthosis nigricans in the knuckles: An early, accessible, straightforward, and sensitive clinical tool to predict insulin resistance Dermato-endocrinology · 2018 · 6 citations
    7. A case of hyperpigmentation and acanthosis nigricans by testosterone injections Human & experimental toxicology · 2014 · 6 citations
    8. Global hotspots and trends in Acanthosis nigricans research: A bibliometric and visualized analysis Skin Research and Technology · 2024 · 3 citations
    9. Mania in Hyperandrogenism, Insulin Resistance, and Nigricans Acanthosis Syndrome ˜The œAmerican journal of psychiatry · 2002 · 3 citations
    10. A case of severe hyperandrogenism, acanthosis nigricans and overt diabetes: the use of non-invasive methods for diagnosis, pathogenesis and management Gynecological endocrinology · 1996 · 1 citations
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