Exosome Therapy for Scalp Hair Growth—A Review of the In Vivo and In Vitro Evidence

    September 2022 in “ Journal of the American Academy of Dermatology ”
    Briana Paiewonsky, Nicole Heinen, Gretchen Bellefeuille, Ora Raymond, Maria Hordinsky, Ron Shapiro, Ronda S. Farah
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    TLDR Exosome therapy shows promise for hair growth but needs human trials for validation.
    The review of preclinical studies on exosome therapy for hair growth analyzed 10 relevant articles, with 9 indicating positive effects on hair growth, such as prolonged anagen phase, increased hair growth, and alterations in hair-related growth factors. The studies included both in vivo (mouse or rat) and in vitro (mouse, goat, or human cells) research. One study on alopecia areata in a C3H/HeJ mouse model showed improvement with exosome use. Despite promising preclinical results, human clinical studies are necessary to confirm the efficacy of exosome therapy for hair growth in humans.
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