Exosome Therapy for Scalp Hair Growth—A Review of the In Vivo and In Vitro Evidence

    September 2022 in “ Journal of the American Academy of Dermatology ”
    Briana Paiewonsky, Nicole Heinen, Gretchen Bellefeuille, Ora Raymond, Maria Hordinsky, Ron Shapiro, Ronda S. Farah
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    TLDR Exosome therapy shows promise for hair growth but needs human trials for validation.
    The review of preclinical studies on exosome therapy for hair growth analyzed 10 relevant articles, with 9 indicating positive effects on hair growth, such as prolonged anagen phase, increased hair growth, and alterations in hair-related growth factors. The studies included both in vivo (mouse or rat) and in vitro (mouse, goat, or human cells) research. One study on alopecia areata in a C3H/HeJ mouse model showed improvement with exosome use. Despite promising preclinical results, human clinical studies are necessary to confirm the efficacy of exosome therapy for hair growth in humans.
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      community How Does Exosome Therapy Work for Hair Loss?

      in Research/Science  5 upvotes 1 year ago
      Exosome hair therapy involves injecting stem cell-derived exosomes into the scalp to boost hair follicle regeneration and repair. Exosomes, which are not stem cells but products of them, contain bioactive chemicals and specific growth factors that promote new blood vessel formation, increase cell proliferation, reduce inflammation, and improve tissue repair, all crucial for hair health.

      community Anyone familiar with Exosome Therapy from Springs Rejuvenation?

      in Treatment  1 upvotes 2 months ago
      A user is considering exosome therapy from Springs Rejuvenation for hair loss after unsuccessful attempts with PRP, adipose injections, and a laser cap. They are intrigued by the therapy's potential and the clinic's guarantee of 30% improved coverage, despite concerns about FDA approval and high-pressure sales tactics.

      community Mesenchymal Stem Cell Therapy (Exosome) Before & After

      in Treatment  2 upvotes 7 months ago
      A user's father experienced hair regrowth and other health improvements after two IV exosome treatments. The user also had four rounds of exosome therapy, noting significant hair regrowth and relief from headaches, but no change in gray hair.

      community Anyone have PRP/Exosome results to share?

      in Treatment  3 upvotes 1 year ago
      Considering alternative treatments to hair loss, such as platelet-rich plasma (PRP) and exosome therapy, instead of using medications like minoxidil, finasteride/dutasteride.

      community Can trichodynia ruin an exosome treatment?

      in Chat  1 upvotes 2 months ago
      The user has tried various hair loss treatments including topical minoxidil, oral finasteride, oral dutasteride, oral minoxidil, and exosome therapy, but none have been effective. They suspect trichodynia might be preventing these treatments from working.

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