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This review discusses regenerative medicine's applications in dermatology, highlighting the need for quality clinical trials to optimize treatments like PRP, stem cells, and exosomes, and reports no new results.

In this study, XZYFD, a Traditional Chinese Medicine formulation, was found to improve androgenetic alopecia in a testosterone-induced mouse model by promoting hair regrowth, restoring follicular morphology, and modulating androgen metabolism, MAPK signaling, and lipid metabolism pathways, suggesting potential benefits for patients with metabolic dysfunction.

This study found that rat hair follicle stem cells can be effectively transfected with VEGF 165 using lentivirus vectors, suggesting their potential use in developing tissue-engineered skin with improved vascularization.

This study found that hypoxic preconditioning of nanofat from donor mice reduced its vascularization capacity in vivo, suggesting that this approach cannot currently enhance nanofat's regenerative potential.

This review collected findings on the various cosmetic and therapeutic properties of tea extracts, highlighting their antioxidant, anti-inflammatory, and photoprotective effects among other benefits for skin and hair care.

In this mouse study, researchers reported that a 3D bioprinted hydrogel scaffold containing adipose-derived mesenchymal stem cells and nitric oxide enhanced burn wound healing by promoting neovascularization through the VEGF signaling pathway.

This review discusses the use of human mesenchymal stem cells (hMSCs) for treating skin diseases and suggests they show promise for improving conditions like wounds and scleroderma, but more research is needed due to varied study designs and endpoints.

This study reviews the roles and mechanisms of MSC-derived exosomes in wound healing, noting their potential as promising cell-free therapies for cutaneous regeneration.

This review discusses the use of stem cells and stem cell-derived products in burn wound healing, highlighting various stem cell sources, associated signaling pathways, and delivery methods, but reports no new clinical results.

This review synthesizes current research on PPAR-γ signaling in hair follicle biology and its potential role in treating hair growth disorders like scarring alopecia and hirsutism, but reports no new clinical results.

This review discusses the challenges of traditional phytochemical delivery methods and highlights the potential of microneedles to improve intra/transdermal delivery, reporting no new clinical results.

This review presents clinical and preclinical evidence supporting innovative regenerative approaches to treat vitiligo, as existing treatments lack a specific cure and predictable long-term repigmentation outcomes.

This study found that sex hormones, specifically non-aromatizable androgens like DHT and A/T, significantly increase inflammatory cytokine expression in human adipocytes when stimulated by LPS.

This study found that fermenting porcine and equine placentas with a specific lactic acid bacterial strain enhanced the moisturizing abilities and cell proliferation properties compared to traditional placental extracts, suggesting their potential for cosmetic applications.

This review discusses the dermatological applications and potential health benefits of Epigallocatechin-gallate (EGCG) from green tea, but provides no new clinical findings.

In a randomized, double-blinded, placebo-controlled clinical trial, this study found that the botanical-based compound ALRV5XR significantly increased hair regrowth in women with androgenetic alopecia or telogen effluvium, with no adverse events reported.

This study reports that human adipose-derived stem cells cultured with platelet lysate instead of fetal bovine serum demonstrate enhanced stress resistance, reduced cellular aging, and faster wound healing in mice, due in part to upregulated stress response and proliferation genes.

This review discusses the potential of mesenchymal stromal cell secretome therapies for facial nerve palsy, emphasizing their standardization advantages over cell transplantation, but provides no new clinical results.

This article examines advancements in understanding and managing androgenic alopecia (male pattern baldness), discussing genetic and psychological factors, diagnostic methods, classifications, and various treatment options, including traditional and emerging therapies, to aid healthcare professionals in making informed treatment decisions.

This study observed that tissue-engineered skin, using VEGF165 gene-modified cells embedded in astragalus polysaccharide-containing 3D printed scaffolds, enhanced early vascularization, and collagen and hair follicle regeneration, leading to improved skin repair in nude mice with full skin defects.

This review explored recent research on the immune mechanisms and potential therapeutic targets for alopecia areata, highlighting the roles of immune-related cells, autocrine and paracrine signaling, as well as factors like adipose-derived stem cells and gut microbiota in disease pathogenesis.

This study suggests that the synthetic peptide SPIKENET (SPK) may protect against long-term skin alterations in mice following coronavirus infection, offering potential therapeutic intervention for similar effects in humans post-COVID-19.

This review highlights exosomes as a promising treatment for skin damage from UV light, infrared radiation, burns, and disorders due to their anti-inflammatory properties, ability to induce macrophage polarization, and acceleration of skin repair and regeneration.

This study found that sustained ERK activity during tissue regeneration in spiny mice is linked to fibroblast growth factor and ErbB signaling, while inhibiting ERK shifted regeneration toward scarring.

This study found that the guided SEFFI technique for facial volume restoration and anti-aging is minimally invasive with a low complication rate, suggesting it as a promising treatment option.

This review reports that oral collagen peptide supplements may improve skin elasticity, hydration, and wrinkle appearance while also supporting hair and nail health and wound healing, but emphasizes the need for longer, high-quality studies due to current research limitations and variability in findings.

This study found that Annexin A5 significantly reduced fibrosis and inflammation in both preventive and therapeutic contexts in a bleomycin-induced localized scleroderma mouse model, demonstrating its potential anti-fibrotic and anti-inflammatory effects for treating fibrotic diseases.

This study found that ethanolic extracts of Buebang 3 CMU may promote hair growth and prevent hair loss more effectively than minoxidil by enhancing bioactive compounds and activating key signaling pathways.

This review highlights various plant-based and herbal treatments that reportedly help prevent hair loss and encourage hair growth. It also explores the molecular mechanisms, identified plant compounds, recent technologies such as nanoarchitectonics, and patents related to hair growth promotion.

This review highlights the potential of nanotechnology for hair follicle regeneration, focusing on strategies such as hair cycle modulation, progenitor cell stimulation, and wound-induced hair neogenesis, while also discussing regulatory challenges that may affect the development of these innovative approaches.