TLDR Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
The study investigates dermatologic changes in mice infected with MHV-1, a model for long COVID. Acute infection led to epidermal destruction, increased hair follicles, collagen deposition, and sebaceous gland hyperplasia. Long-term effects included hair follicle loss, adipose tissue destruction, and further epidermal damage. Treatment with the synthetic peptide SPIKENET (SPK) demonstrated protective effects, restoring hair follicles, re-architecting skin layers, and repairing fatty tissue damage. The study involved 16 mice for acute phase observations and 6 mice for long-term and treatment evaluations. These results suggest SPK's potential as a therapeutic intervention for preventing long-term skin alterations caused by SARS-CoV-2.
February 2023 in “Journal of Drugs in Dermatology” Melatonin may help improve hair growth in people with certain types of hair loss.
14 citations,
December 2021 in “International journal of molecular sciences” Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.
102 citations,
July 2020 in “International journal of molecular sciences” Hormones like testosterone and estrogen significantly affect hair growth and structure.
24 citations,
June 2018 in “PubMed” Serenoa repens extract helps regrow hair and repair hair loss by activating certain cell growth pathways.
29 citations,
August 2017 in “Skin appendage disorders” IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.
12 citations,
December 2016 in “PubMed” 34 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Human hair growth is influenced by androgen hormones, and red deer mane follicles have similar hormone receptors.
17 citations,
May 2015 in “Nanomedicine: Nanotechnology, Biology and Medicine” Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.
28 citations,
December 2011 in “Biocatalysis and biotransformation” PDI helps restore over-bleached hair's strength and structure by attaching special peptides.
125 citations,
August 2020 in “Frontiers in Immunology” Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
January 2024 in “Journal of Ayurveda Campus” Psoralea corylifolia Linn. is a medicinal plant used for skin diseases and has various health benefits.
6 citations,
March 2022 in “Frontiers in drug discovery” Some small molecule antivirals show promise against COVID-19, but more research is needed to understand and improve them.
