June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
2 citations,
June 2022 in “Cells” 3D cell cultures are better for testing hair growth treatments than 2D cultures.
46 citations,
September 2014 in “Tissue engineering. Part A” Researchers created hair-inducing human cell clusters using a 3D culture method.
29 citations,
April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
16 citations,
August 2019 in “Cell Proliferation” Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
1 citations,
March 2024 in “Nanomaterials” Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
Scientists improved how to grow mouse skin cells in the lab and created a long-lasting cell line, but didn't fully explain its advantages or compare it to normal cells.
55 citations,
April 2017 in “Experimental Dermatology” The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.
61 citations,
December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
5 citations,
September 2021 in “Frontiers in Cell and Developmental Biology” Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.
1 citations,
January 2023 in “Burns and trauma” Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.
December 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Scientists found a new method using 3D cell cultures to grow human hair which may improve hair restoration treatments.
January 2024 in “Biomaterials Research” 3D-cultured cells in HGC-coated environments improve hair growth and skin integration.
62 citations,
February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
2 citations,
April 2021 in “International Journal of Molecular Sciences” The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
November 2023 in “Materials Today Bio” Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
39 citations,
April 2019 in “Journal of Biomaterials Science, Polymer Edition” RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
9 citations,
November 2019 in “Scientific reports” The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
November 2022 in “Regenerative Therapy” Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
35 citations,
January 2020 in “Skin Pharmacology and Physiology” The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
10 citations,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
3 citations,
January 2017 in “Methods in molecular biology” The book explains how to grow and repair organs using new lab techniques.
83 citations,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
7 citations,
June 2021 in “Cell Proliferation” Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
19 citations,
January 2017 in “Stem Cells International” Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
January 2022 in “Stem cell biology and regenerative medicine” Improving dermal papilla cells can help regenerate hair follicles.
16 citations,
July 2020 in “Advanced functional materials” 3D cell-derived matrices improve tissue regeneration and disease modeling.
6 citations,
October 2020 in “Journal of Cellular and Molecular Medicine” 3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.