research Cyclic Cushing Syndrome Caused By An ACTH-Producing Pheochromocytoma
A woman's cyclic Cushing syndrome was caused by a tumor in her adrenal gland that produced ACTH.
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research Design, Synthesis, and Preclinical Evaluation of Prostate-Specific Membrane Antigen Targeted 99mTc-Radioimaging Agents
Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research Unmet Medical Needs in Chronic, Non-Communicable Inflammatory Skin Diseases
There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
research The Pharmacology of Regenerative Medicine
Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
research Design and Synthesis of Novel Androgen Receptor Antagonists with Sterically Bulky Icosahedral Carboranes
New compounds with carborane showed anti-androgen effects similar to flutamide.
research Nonsurgical Management of Facial Masculinization and Feminization
Injectables can feminize or masculinize a transgender person's face, but more research is needed for best practices.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Polycystic Ovary Syndrome in Adolescence and Type 2 Diabetes
Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.
research The Hirsute Woman: Challenges in Evaluation and Management
Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.
research Novel Aspects of Age-Protection by Spermidine Supplementation Are Associated with Preserved Telomere Length
Spermidine helps protect against aging by preserving telomere length.
research In Vivo Monitoring of Hair Cycle Stages via Bioluminescence Imaging of Hair Follicle NG2 Cells
Bioluminescence imaging can track hair follicle cells and help study hair regrowth.
research Medical Dermatologic Conditions in Transgender Women
Hormone therapy in transgender women can affect hair growth and acne, and there are specific skin issues related to gender-affirming surgery, but more research is needed on their dermatological health.
research An Ovarian Leydig Cell Tumor Undetected by Ultrasound in a Postmenopausal Woman with Hirsutism and Hyperandrogenism
A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.
research Systemic Autoimmune Diseases: Insights and Advances
The document concludes that systemic autoimmune diseases are complex, incurable, and require ongoing treatment and research.
research Stem Cell Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies
Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
research Elicitor Mediated Enhancement of Wedelolactone in Cell Suspension Culture of Eclipta Alba (L.) Hassk
Adding yeast extract and methyl jasmonate to Eclipta alba cell cultures increased the production of the compound wedelolactone.
research The Charnoly Body as a Universal Biomarker of Cell Injury
Charnoly bodies could be a marker for cell damage, and certain nutrients and proteins might prevent them, potentially helping with brain diseases and cancer.
research Theoretical Evaluation of Interaction of Some Dibenzo Derivatives on Both Androgen Receptor and 5-Alpha-Reductase Enzyme
Certain Dibenzo derivatives may help treat prostate cancer.
research Imaging Prostate Cancer With Technetium-99m Tricarbonyl Finasteride Dithiocarbamate
A new compound was effective for imaging prostate cancer in rats.
research Alopecia Areata Associated with Thymoma Presenting as a Diffuse Pleural Dissemination Mimicking Mesothelioma: Rare Concomitant Presentation
A rare case showed hair regrowth after chemotherapy for thymoma, suggesting a link between alopecia areata and thymoma.
research Mucosal TLR5 Activation Controls Healthspan and Longevity
Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
research The Effects of Low-Dose Radiation Therapy in Patients With Mild-to-Moderate Alzheimer's Dementia: An Interim Analysis of a Pilot Study
Low-dose radiation therapy may improve brain function in some Alzheimer's patients and is generally well-tolerated.
research Generating Detailed Intercellular Communication Patterns in Psoriasis at the Single-Cell Level Using Social Networking, Pattern Recognition, and Manifold Learning Methods to Optimize Treatment Strategies
New insights into cell communication in psoriasis suggest innovative drug treatments.
research Brown Adipose Tissue as an Innovative Approach for Polycystic Ovary Syndrome Treatment: A Narrative Review
More research is needed before using brown fat to treat polycystic ovary syndrome.
research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going
Innovative methods are reducing animal testing and improving biomedical research.
research Defining Metabolic Flexibility in Hair Follicle Stem Cell Induced Squamous Cell Carcinoma
Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.
research Non-Coding Double Stranded RNA Induces Retinoic Acid Synthesis and Retinoid Signaling to Control Regeneration
Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
research Effects of Altering Allopregnanolone Levels During Critical Neurodevelopmental Periods on Alcohol Consumption Vulnerability
Early NAS level changes affect alcohol consumption vulnerability.
research Spironolactone
Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.