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The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

The method accurately measures 19 steroid hormones in human blood and urine using a small sample and is suitable for large-scale monitoring.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Women with effluvium have higher levels of certain urinary steroids, possibly due to stress and increased adrenal activity.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

New hair growth corticosterone levels are higher in diabetic mice, indicating long-term stress.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.

The glucocorticoid receptor helps protect skin from tumors and other issues.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

THCCOOH levels in hair decrease from root to tip and don't match well with self-reported cannabis use.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.