Urinary Steroid Analysis of Women with Effluvium

July 1998 in “ Chromatographia ”

Enikő Telegdy, S. Juricskay

effluvium urinary steroid metabolites adrenal gland cortisol steroid metabolism hormonal changes hair loss stress hormones

TLDR Women with effluvium have higher levels of certain urinary steroids, possibly due to stress and increased adrenal activity.

In a study conducted on 25 women with effluvium (average age 33.3 ± 12.0 years) and compared to 16 healthy control women (average age 34.6 ± 8.4 years), researchers found significant elevations in the levels of various urinary steroid metabolites. The study suggested that these elevations indicate increased steroid secretion from the adrenal gland and that high cortisol metabolite levels may be related to stress in some patients with effluvium. The results also highlighted the importance of examining urinary steroid excretion in patients with hair loss, as it provides a broad view of hormonal changes and potential sources of alterations in steroid metabolism. The study concluded that urinary steroid metabolite analysis could offer valuable insights into the metabolic changes associated with effluvium.

View this study on link.springer.com →

Discuss this study in the Community →

Research cited in this study

3 / 3 results

research Androgenic Disorders of Women: Diagnostic and Therapeutic Decision Making

17 citations , January 1995 in “The American Journal of Medicine”

The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.

research Hormonal Basis of Male and Female Androgenic Alopecia: Clinical Relevance

23 citations , January 1994 in “Skin Pharmacology and Physiology”

Hair loss in men and women is linked to high stress hormone levels and other hormonal imbalances, suggesting treatments should be customized to each person's hormones.

research The Metabolism of Dehydroepiandrosterone by Human Scalp Hair Follicles

28 citations , March 1973 in “The Journal of Clinical Endocrinology & Metabolism”

Altered DHEA metabolism in hair follicles may be linked to hair loss in balding men.

Related Community Posts Join

6 / 616 results

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The link between hair loss and gut health

in Research/Science 59 upvotes 5 years ago

The conversation discusses the potential link between gut health and hair loss, with personal experiences of hair thinning and stomach issues shared. Some individuals found no success with common hair loss treatments like Minoxidil and Finasteride and are exploring the impact of gut health on hair growth.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 101 upvotes 4 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.

in Research/Science 10 upvotes 1 year ago

Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.

community I think we all hop on estrogen. It's the only angle

in Satire 83 upvotes 1 year ago

The conversation humorously discusses hair loss treatments, including Minoxidil, finasteride, RU58841, and topical 17 alpha estradiol, with some users joking about transitioning to female to avoid baldness. The overall tone is satirical, emphasizing self-acceptance and the lengths people might consider for hair restoration.

community ~3.5 Months on daily oral dut 0.5mg, oral min 2.5mg, topical RU 80mg, weekly microneedling at 1.5mm

in Progress Pictures 34 upvotes 3 years ago

The conversation is about a 23-year-old who started treating their hair loss with daily oral dutasteride (0.5mg), oral minoxidil (2.5mg), topical RU58841 (80mg), and weekly microneedling at 1.5mm after seeing others' success stories. Significant improvements have been noted, and there is optimism for even better results in the next 6 months.

Similar Research

5 / 1000+ results

research Hyperadrenocorticism (Cushing’s Disease or Syndrome) in Dogs: Treatment Approaches and Prognosis

23 citations , February 1979 in “Veterinary Clinics of North America: Small Animal Practice”

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

research Androgenic Alopecia in Females: Diagnosis and Treatment

14 citations , July 1987 in “Dermatologic Clinics”

The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.

research Endocrine-Skin Interactions

46 citations , July 1988 in “Journal of The American Academy of Dermatology”

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

research Hair Loss in Women: Comprehensive Overview and Treatment Options

81 citations , March 2009 in “Seminars in Cutaneous Medicine and Surgery”

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

research Potential Factors Contributing to Androgenetic Alopecia

8 citations , January 1996 in “Springer eBooks”

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.