Utilizing SNP Association Analysis as a Prospective Approach for Personalizing Androgenetic Alopecia Treatment

March 2024 in “ Dermatology and therapy (Internet) ”

Maria F. Frances, Laura Vila-Vecilla, Valentina Russo, Hudson Polonini, Gustavo Torres de Souza

androgenetic alopecia single nucleotide polymorphisms SNPs genetic data personalized treatment therapeutic responses AGA genetic variations

TLDR Genetic factors could lead to personalized treatments for hair loss.

The study analyzed the genetic data of 26,607 patients with Androgenetic Alopecia (AGA), finding that 64.6% of males and 35.4% of females were diagnosed with AGA. The research identified eight specific single nucleotide polymorphisms (SNPs) that were statistically significant in relation to AGA. These SNPs could provide insights into the variability of therapeutic responses, emphasizing the potential for personalized treatment approaches for AGA. The study suggests that understanding these genetic factors could help in developing personalized therapeutic strategies for AGA, although further research is needed to validate these findings.

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