Therapeutic Update on Alopecia Areata: A Critical Review of Standard and Emerging Targeted Therapies

    May 2026 in “ Inflammopharmacology ”
    Francesco Ferrara
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    Research cited in this study 43

    1. Baricitinib Withdrawal and Retreatment in Patients With Severe Alopecia Areata JAMA Dermatology · 2024
    2. Expecting Scalp Hair Regrowth During Severe Alopecia Areata Treatment with Baricitinib: Insights from Patient Trajectories in Phase III Trials British Journal of Dermatology · 2023
    3. Baricitinib: A Review in Severe Alopecia Areata American Journal of Clinical Dermatology · 2023
    4. Alopecia Areata: An Updated Review for 2023 Journal of Cutaneous Medicine and Surgery · 2023
    5. Efficacy of Baricitinib in Patients With Various Degrees of Alopecia Areata Severity: Results From Brave-AA1 and Brave-AA2 Journal of The American Academy of Dermatology · 2022
    6. Lifestyle Factors Involved in the Pathogenesis of Alopecia Areata International journal of molecular sciences · 2022
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    8. Treatment of Pediatric Alopecia Areata: A Systematic Review Journal of the American Academy of Dermatology · 2021
    9. A Phase 2a Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of the Oral Janus Kinase Inhibitors Ritlecitinib and Brepocitinib in Alopecia Areata: 24-Week Results Journal of the American Academy of Dermatology · 2021
    10. The Role of Diet as an Adjuvant Treatment in Scarring and Nonscarring Alopecia Skin appendage disorders · 2020
    11. Benefit and Risk Profile of Tofacitinib for the Treatment of Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the European Academy of Dermatology and Venereology · 2019
    12. Weekly Azathioprine Pulse Versus Betamethasone Oral Mini-Pulse in the Treatment of Moderate-to-Severe Alopecia Areata Indian Journal of Dermatology · 2019
    13. Treatment of Chronic Extensive Alopecia Areata by Diphenylcyclopropenone Alone Versus in Combination with Anthralin Dermatologic therapy · 2019
    14. JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    15. Dupilumab Improved Alopecia Areata in a Patient with Atopic Dermatitis: A Case Report Acta Dermato Venereologica · 2019
    16. Janus Kinase Inhibitors for the Treatment of Severe Alopecia Areata: An Open-Label Comparative Study Dermatology · 2018
    17. Response to Tofacitinib Therapy of Eyebrows and Eyelashes in Alopecia Areata Journal of the American Academy of Dermatology · 2018
    18. A Randomized Placebo-Controlled Single-Center Pilot Study of the Safety and Efficacy of Apremilast in Subjects with Moderate-to-Severe Alopecia Areata Archives of dermatological research · 2018
    19. Treatment of Alopecia Areata: An Australian Expert Consensus Statement Australasian journal of dermatology · 2018
    20. Response to Ustekinumab in Three Pediatric Patients with Alopecia Areata Pediatric dermatology · 2018
    21. Role of Janus Kinase Inhibitors in the Treatment of Alopecia Areata Drug design, development and therapy · 2018
    22. Vitamin D Deficiency in Patients With Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the American Academy of Dermatology · 2017
    23. The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm Advances in Therapy · 2017
    24. JAK Inhibitors in Dermatology: The Promise of a New Drug Class Journal of the American Academy of Dermatology · 2017
    25. Platelet-Rich Plasma Versus Minoxidil 5% in Treatment of Alopecia Areata: A Trichoscopic Evaluation Dermatologic Therapy · 2016
    26. Efficacy and Safety of Superficial Cryotherapy for Alopecia Areata: A Retrospective Comprehensive Review of 353 Cases Over 22 Years The Journal of Dermatology · 2016
    27. Pharmacologic Inhibition of JAK-STAT Signaling Promotes Hair Growth Science Advances · 2015
    28. Inhibiting Janus Kinases to Treat Alopecia Areata Nature medicine · 2014
    29. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    30. Dermoscopic Evaluation of Therapeutic Response to an Intralesional Corticosteroid in the Treatment of Alopecia Areata Indian Journal of Dermatology, Venereology and Leprology · 2013
    31. Systemic Treatment for Alopecia Areata Dermatologic therapy · 2011
    32. Treatment of Alopecia Areata: What Is New on the Horizon? Dermatologic therapy · 2011
    33. Intralesional Steroids for Alopecia Areata International Journal of Trichology · 2010
    34. Phase I/II Randomized Bilateral Half-Head Comparison of Topical Bexarotene 1% Gel for Alopecia Areata Journal of the American Academy of Dermatology · 2009
    35. 308-nm Excimer Laser for the Treatment of Alopecia Areata in Children Pediatric dermatology · 2009
    36. Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia in a C3H/HeJ Mouse Model ˜The œAmerican journal of pathology · 2008
    37. Genomewide Scan for Linkage Reveals Evidence of Several Susceptibility Loci for Alopecia Areata The American Journal of Human Genetics · 2007
    38. Restoration of Hair Growth in Mice with an Alopecia Areata-Like Disease Using Topical Anthralin Experimental Dermatology · 2004
    39. Clobetasol Propionate 0.05% Under Occlusion in the Treatment of Alopecia Totalis/Universalis Journal of the American Academy of Dermatology · 2003
    40. Efficacy of Topical Sensitizers in the Treatment of Alopecia Areata Journal of the American Academy of Dermatology · 1998
    41. Topical Photochemotherapy for Alopecia Areata Journal of the American Academy of Dermatology · 1985
    42. Topical Minoxidil in the Treatment of Alopecia Areata BMJ · 1983
    43. Large Doses of Glucocorticoid in the Treatment of Alopecia Areata Acta dermato-venereologica · 1975