Systemic Treatment for Alopecia Areata

May 2011 in “ Dermatologic therapy ”

Nina Otberg

TLDR Effective treatments for severe alopecia areata are still lacking.

Alopecia areata affected 1.7% of the global population at some point in their lives, with an unknown etiology and unpredictable course. Effective treatments for severe forms, such as multifocal alopecia areata, alopecia areata totalis, and alopecia areata universalis, were lacking. The article discussed the side effects and relapse rates of various systemic agents used to treat severe and rapidly progressing alopecia areata.

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9 / 9 results

research Alopecia Areata Update

391 citations , February 2010 in “Journal of The American Academy of Dermatology”

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

research Alopecia Areata Following Adalimumab

38 citations , January 2009 in “Journal of Cutaneous Medicine and Surgery”

A woman developed hair loss after starting a treatment with adalimumab, suggesting this medication might cause hair loss.

research Treatment of Persistent Alopecia Areata with Sulfasalazine

45 citations , July 2008 in “International Journal of Dermatology”

Sulfasalazine may help treat persistent alopecia areata.

research Development of Alopecia Areata Universalis in a Patient Receiving Adalimumab

69 citations , December 2006 in “Archives of dermatology”

Adalimumab may cause severe hair loss in some patients.

research Alopecia Areata Presenting in Two Kidney-Pancreas Transplant Recipients Taking Cyclosporine

23 citations , November 2005 in “Journal of The American Academy of Dermatology”

Two transplant patients on cyclosporine unexpectedly developed hair loss.

research Treatment of Hair Loss

370 citations , September 1999 in “The New England Journal of Medicine”

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

research Alopecia Areata in a Renal Transplant Recipient on Cyclosporin

12 citations , November 1996 in “Australasian journal of dermatology”

A kidney transplant patient on cyclosporin experienced unexpected severe hair loss, which improved with treatment adjustments.

research Alterations in scalp blood flow after the epicutaneous application of 3% minoxidil and 0.1% hexyl nicotinate in alopecia

25 citations , November 1987 in “British Journal of Dermatology”

Minoxidil didn't increase scalp blood flow for hair growth, but hexyl nicotinate did.

research Large doses of glucocorticoid in the treatment of alopecia areata

80 citations , November 1975 in “Acta dermato-venereologica”

Large doses of glucocorticoids are not suitable for general use in treating severe alopecia areata due to inconsistent results and risks.

4 / 4 results

research Alopecia Areata: A Multifactorial Autoimmune Condition

148 citations , March 2019 in “Journal of autoimmunity”

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

research Case Report of Novel Combination of Anthralin and Calcipotriene Leading to Trichologic Response in Alopecia Areata

6 citations , March 2019 in “JAAD case reports”

A new mix of anthralin and calcipotriene might help treat severe hair loss.

research Linear Alopecia Areata

4 citations , November 2018 in “JAAD case reports”

Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.

research Treating Resistant Cases of Alopecia Universalis

May 2018 in “Journal of cosmetology & trichology”

Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.