717 citations
,
June 2010 in “Nature” This study identified key genetic regions associated with alopecia areata, highlighting both acquired and innate immune involvement, with a novel link to the upregulation of ULBP ligands in autoimmune disease.
391 citations
,
January 2010 in “Journal of The American Academy of Dermatology” This article reviews the clinical presentation and histopathologic features of alopecia areata and proposes a hypothesis for its development, but it reports no new clinical results.
38 citations
,
January 2009 in “Journal of Cutaneous Medicine and Surgery” This case report highlights a woman who developed new-onset alopecia areata after starting adalimumab for psoriatic arthritis, challenging the assumed role of TNF-alpha in the condition's pathogenesis.
45 citations
,
July 2008 in “International Journal of Dermatology” This study found that oral sulfasalazine led to varying hair regrowth outcomes in patients with persistent alopecia areata, with 56.3% showing moderate to good responses.
69 citations
,
December 2006 in “Archives of dermatology” This entry contains no research abstract, so no scientific findings or conclusions are reported.
100 citations
,
July 2006 in “British Journal of Dermatology” This study found that intralesional triamcinolone acetonide injections using a needleless injector led to rapid hair regrowth in patients with limited alopecia areata, while lasting growth was rare in alopecia totalis.
97 citations
,
January 2006 in “Dermatology” This study found that intramuscular triamcinolone acetonide or pulse therapy effectively treats alopecia areata with manageable side effects, but further strategies are needed to reduce relapse rates.
23 citations
,
October 2005 in “Journal of The American Academy of Dermatology” This report describes the unexpected development of alopecia areata in kidney-pancreas transplant recipients undergoing cyclosporine-based immunosuppressive therapy, suggesting a complex relationship between the treatment and disease.
75 citations
,
June 2005 in “Archives of Dermatology” In this case report, a patient experienced a recurrence of alopecia areata while undergoing etanercept treatment, suggesting the drug may not effectively prevent this condition's return.
141 citations
,
February 2005 in “Journal of the American Academy of Dermatology” In this study, oral prednisolone pulse therapy led to significant hair regrowth in some patients with extensive alopecia areata, whereas no improvement was seen in the placebo group.
370 citations
,
September 1999 in “The New England Journal of Medicine” This article discusses the treatment of androgenetic alopecia and alopecia areata with finasteride and minoxidil but reports no new clinical results.
12 citations
,
November 1996 in “Australasian journal of dermatology” A kidney transplant patient on cyclosporin experienced unexpected severe hair loss, which improved with treatment adjustments.
117 citations
,
February 1996 in “International Journal of Dermatology” This study found that monthly oral prednisolone pulses of 300 mg were effective and safe for treating widespread alopecia areata, with 58.3% of patients achieving cosmetically acceptable hair growth.
24 citations
,
November 1992 in “Archives of Dermatology” This study found that a 6-week taper of prednisone led to more than 25% hair regrowth in 30% to 47% of alopecia areata patients, and applying 2% topical minoxidil helped maintain this growth.
25 citations
,
November 1987 in “British Journal of Dermatology” This study observed increases in scalp blood flow following the application of 3% minoxidil and 0.1% hexyl nicotinate in individuals with alopecia.
80 citations
,
November 1975 in “Acta dermato-venereologica” This study found that while some patients with severe alopecia areata responded to high-dose prednisolone, the response was inconsistent and the therapy's risks prevent recommending it for general use.
