Weekly Azathioprine Pulse Versus Betamethasone Oral Mini-Pulse in the Treatment of Moderate-to-Severe Alopecia Areata

    July 2019 in “ Indian Journal of Dermatology ”
    Saurabh Singh, Prashant Gupta, Sujay Khandpur, Neetu Bhari
    TLDR Weekly azathioprine pulse is a better alternative to corticosteroids for treating alopecia areata due to fewer side effects.
    The study compared weekly azathioprine pulse (WAP) therapy and betamethasone oral mini-pulse therapy in treating moderate-to-severe alopecia areata in 60 patients. Both treatments were effective, but the azathioprine group showed a slightly higher improvement rate and fewer side effects. At 9 months, 50% of patients in the WAP group and 62% in the betamethasone group achieved complete hair regrowth. Betamethasone caused more side effects, including facial puffiness, weight gain, and steroid acne. The study concluded that WAP could be a better alternative due to its lower side effect profile, though further research was recommended.
    Discuss this study in the Community →

    Research cited in this study

    12 / 12 results

    Related Community Posts Join

    1 / 1 results

      community Not everyone should immediately go on Fin if they are starting to bald

      in Finasteride/Dutasteride  21 upvotes 2 years ago
      The conversation suggests that people should consult a dermatologist to understand their type of hair loss before starting treatments like finasteride or dutasteride, especially if they have autoimmune issues or low DHT. Some participants believe in starting treatment like finasteride immediately if hair loss is due to DHT, while others recommend ruling out other causes and considering minoxidil first, especially for younger individuals.

    Related Research

    1 / 1 results