Weekly Azathioprine Pulse Versus Betamethasone Oral Mini-Pulse in the Treatment of Moderate-to-Severe Alopecia Areata

    July 2019 in “ Indian Journal of Dermatology ”
    Saurabh Singh, Prashant Gupta, Sujay Khandpur, Neetu Bhari
    Studysummary This study found that azathioprine pulse therapy and betamethasone both effectively managed alopecia areata with similar hair regrowth results, though betamethasone had significantly more side effects, suggesting azathioprine as a preferable alternative to corticosteroids.
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    Research cited in this study 13

    1. Chronological Clinicopathological Characterization of Rapidly Progressive Alopecia Areata Resistant to Multiple Intravenous Corticosteroid Pulse Therapies: An Implication for Improving Efficacy The Journal of Dermatology · 2018
    2. Multiple Courses of Pulse Corticosteroid Therapy for Alopecia Areata The Journal of Dermatology · 2016
    3. A Systematic Review of Pulse Steroid Therapy for Alopecia Areata Journal of the American Academy of Dermatology · 2016
    4. A Comparative Study of Oral Cyclosporine and Betamethasone Minipulse Therapy in the Treatment of Alopecia Areata Annals of dermatology/Annals of Dermatology · 2016
    5. Combined Oral Pulse and Topical Corticosteroid Therapy for Severe Alopecia Areata in Children: A Long-Term Follow-Up Study Dermatologic therapy · 2015
    6. Intravenous Methylprednisolone Pulse Therapy in Severe Alopecia Areata Indian journal of dermatology, venereology, and leprology · 2015
    7. Comparison of High-Dose Corticosteroid Pulse Therapy and Combination Therapy Using Oral Cyclosporine with Low-Dose Corticosteroid in Severe Alopecia Areata Annals of dermatology/Annals of Dermatology · 2015
    8. Combination Therapy With Oral PUVA and Corticosteroid for Recalcitrant Alopecia Areata Archives of dermatological research · 2009
    9. Extensive Alopecia Areata Treated With Betamethasone Oral Mini-Pulse Therapy: An Open Uncontrolled Study PubMed · 2007
    10. Placebo-Controlled Oral Pulse Prednisolone Therapy in Alopecia Areata Journal of the American Academy of Dermatology · 2005
    11. Twice Weekly 5 mg Dexamethasone Oral Pulse in the Treatment of Extensive Alopecia Areata The Journal of Dermatology · 1999
    12. Pulsed Administration of Corticosteroids in the Treatment of Alopecia Areata International Journal of Dermatology · 1996
    13. Systemic Steroids With or Without 2% Topical Minoxidil in the Treatment of Alopecia Areata Archives of Dermatology · 1992

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