Synergistic Effects of Rhynchosia Nulubilis and Polygonum Multiflorum Extract Combination on Cell Proliferation via Targeting IGFBP-1 and NT-3 and Cytotoxicity Suppression in Testosterone-Induced Human Dermal Papilla Cells

    May 2025 in “ PLoS ONE ”
    Jiwon Seo, Chanhyeok Jeong, Jung Han Yoon Park … Ki Won Lee
    Studysummary This study found that a 4:1 combination of Rhynchosia nulubilis and Polygonum multiflorum extracts significantly promoted the proliferation of human dermal papilla cells and alleviated testosterone-induced cytotoxicity, suggesting potential for treating hair loss and related disorders through a synergistic approach.
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    Research cited in this study 21

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