Promotion Effect of Constituents from the Root of Polygonum Multiflorum on Hair Growth

    July 2013 in “ Bioorganic & Medicinal Chemistry Letters ”
    Ya Nan Sun, Long Cui, Wei Li … Young Ho Kim
    Studysummary This study found that compound 2 from Polygonum multiflorum significantly increased dermal papilla cell proliferation and hair-fiber length, suggesting potential as a therapeutic agent for alopecia.
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    Research cited in this study 17

    1. Hair Growth-Promoting Effect of Aconiti Ciliare Tuber Extract Mediated by the Activation of Wnt/β-Catenin Signaling Life Sciences · 2012
    2. Promotion Effect of Acankoreoside J, a Lupane-Triterpene in Acanthopanax Koreanum, on Hair Growth Archives of Pharmacal Research · 2012
    3. Topical Application of Polygonum Multiflorum Extract Induces Hair Growth of Resting Hair Follicles Through Upregulating Shh and β-Catenin Expression in C57BL/6 Mice Journal of Ethnopharmacology · 2011
    4. Finasteride-Induced Secondary Infertility Associated with Sperm DNA Damage Fertility and Sterility · 2011
    5. Hair Loss in Long-Term or Home Parenteral Nutrition: Are Micronutrient Deficiencies to Blame? Current Opinion in Clinical Nutrition & Metabolic Care · 2010
    6. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010
    7. Human Hair Follicles Contain Two Forms of ATP-Sensitive Potassium Channels, Only One Sensitive to Minoxidil The FASEB Journal · 2008
    8. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    9. Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999
    10. Treatment of Hair Loss The New England Journal of Medicine · 1999
    11. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    12. Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia Dermatologic Clinics · 1996
    13. Allergic Contact Dermatitis from Minoxidil Contact Dermatitis · 1995
    14. Transfection of Rat Dermal Papilla Cells with a Gene Encoding a Temperature-Sensitive Polyomavirus Large T Antigen Generates Cell Lines Retaining a Differentiated Phenotype Journal of Cell Science · 1994
    15. Rat Hair Follicle Growth In Vitro British Journal of Dermatology · 1992
    16. The Psychological Effects of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 1992
    17. Hypertrichosis Due to Minoxidil British Journal of Dermatology · 1979

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