Thoughts on this topical? Has a combination going on but are they really heavy hitters
    1/31/2026

    From the encyclopedia
    RU58841 →

    a potent but unapproved and potentially problematic topical anti-androgen

    Caffeine →

    the stimulant you know and love can be used topically to stimulate hair

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 RU58841 (topical) 5% w/v
    💧 AHK-Cu (topical) 1%
    💧 GHK-Cu Peptide (topical) 1%
    💧 Caffeine (topical) 2%
    💧 D-Biotin (topical) 1%
    💧 Methylene Blue (topical) 0.1%
    💧 Keratin (topical) 1%
    💧 Spermidine (topical) 1%
    the tone is 😐 neutral.

    Other terms

    Follicium XR™ is a topical treatment for hair loss containing RU58841, AHK-Cu, GHK-Cu Peptide, caffeine, D-Biotin, methylene blue, keratin, and spermidine. RU58841 is considered the most effective ingredient, but concerns exist about its stability in water.
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