Platelet-Rich Plasma for the Treatment of Alopecia: A Systematic Review and Meta-Analysis

    January 2023 in “ PubMed ”
    Mario Cruciani, Francesca Masiello, Ilaria Pati, Giuseppe Carlo Marano, Simonetta Pupella, Vincenzo De Angelis
    TLDR PRP might help with hair growth, but the evidence is weak.
    This systematic review and meta-analysis evaluated the efficacy of platelet-rich plasma (PRP) in treating androgenetic alopecia (AGA) and alopecia areata (AA) by analyzing 27 controlled trials involving 1,117 subjects. The results showed that PRP injections increased hair density compared to saline injections (MD, 25.6 hairs/cm²; 95% CI: 2.62-48.57) in AGA patients, but the evidence was rated as low quality due to inconsistency and risk of bias. For AA patients, the benefit of PRP compared to triamcinolone injections was unclear, with very low-quality evidence. No serious adverse events were reported. Overall, the evidence supporting PRP's benefit for alopecia treatment is limited and of low quality.
    Discuss this study in the Community →

    Research cited in this study

    41 / 41 results

    Related Community Posts Join

    6 / 89 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 8 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 7 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community When are we getting a cure to hair loss?

      in Chat 2 years ago
      Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

      community Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

      in Research/Science  3 upvotes 1 year ago
      The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

    Related Research

    4 / 4 results