Autologous Platelet-Rich Plasma Therapy for Pattern Hair Loss: A Systematic Review

August 2019 in “ Journal of Cosmetic Dermatology ”

Gezim Dervishi, Haibo Liu, Sandra Peternel, Alexander Labeit, Frank Peinemann

autologous platelet-rich plasma PRP pattern hair loss hair density placebo growth factor levels

Studysummary This study found that autologous platelet-rich plasma was associated with increased hair density in people with pattern hair loss, but with considerable variability and unclear risks of bias.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The systematic review evaluated the efficacy and safety of autologous platelet-rich plasma (PRP) therapy in treating pattern hair loss, analyzing 13 randomized controlled trials with 343 participants. The review found that PRP treatment was associated with an increase in hair density, with a mean difference of 30.35 hairs per square centimeter compared to placebo or no treatment, although the results showed considerable heterogeneity and potential bias. No serious adverse events were reported. The evidence suggested that PRP could be a beneficial low-risk intervention for pattern hair loss, but the review called for more rigorous trials to confirm these findings and to understand the underlying mechanisms, as the increase in hair density was not correlated with platelet count or growth factor levels.

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