Exosomes for Hair Growth and Regeneration

    November 2023 in “ Journal of Bioscience and Bioengineering ”
    Yinghui Zhou, Jieun Seo, S.T. Tu … Junji Fukuda
    Studysummary This review highlights the potential of exosomes, particularly their microRNA components, as promising candidates for developing effective hair loss treatments by exploring their roles in hair follicle development and regeneration.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 26

    1. Comparison of Oral Minoxidil, Finasteride, and Dutasteride for Treating Androgenetic Alopecia Journal of Dermatological Treatment · 2022
    2. Effects of the PI3K/Akt Signaling Pathway on the Hair Inductivity of Human Dermal Papilla Cells in Hair Beads Journal of Bioscience and Bioengineering · 2022
    3. Electrical Stimulation to Human Dermal Papilla Cells for Hair Regenerative Medicine Journal of Bioscience and Bioengineering · 2022
    4. Adipose-Derived Stem Cell Exosomes Promoted Hair Regeneration Tissue Engineering and Regenerative Medicine · 2021
    5. Exosomes Derived from Fisetin-Treated Keratinocytes Mediate Hair Growth Promotion Nutrients · 2021
    6. Impact of Adipose-Derived Stem Cells on Engineering Hair Follicle Germ-Like Tissue Grafts for Hair Regenerative Medicine Journal of Bioscience and Bioengineering · 2021
    7. Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling Science Advances · 2020
    8. Human Hair Outer Root Sheath Cells and Platelet-Lysis Exosomes Promote Hair Inductivity of Dermal Papilla Cells Tissue Engineering and Regenerative Medicine · 2020
    9. Extracellular Vesicles from Activated Dermal Fibroblasts Stimulate Hair Follicle Growth Through Dermal Papilla-Secreted Norrin Stem cells · 2019
    10. MiR-218-5p Regulates Skin and Hair Follicle Development Through Wnt/β-Catenin Signaling Pathway by Targeting SFRP2 Journal of cellular physiology · 2019
    11. Exosomes Derived from Human Dermal Papilla Cells Promote Hair Growth in Cultured Human Hair Follicles and Augment the Hair-Inductive Capacity of Cultured Dermal Papilla Spheres Experimental Dermatology · 2019
    12. Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation International journal of biological sciences · 2019
    13. Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells Biochemical and Biophysical Research Communications · 2018
    14. Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice Scientific Reports · 2017
    15. Spontaneous Hair Follicle Germ Formation In Vitro, Enabling The Large-Scale Production Of HFGs For Regenerative Medicine Biomaterials · 2017
    16. Getting to the Core of the Dermal Papilla Journal of Investigative Dermatology · 2017
    17. MicroRNAs in Skin Tissue Engineering Advanced drug delivery reviews · 2015
    18. MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway Journal of Cell Biology · 2014
    19. Human Epithelial Hair Follicle Stem Cells and Their Progeny: Current State of Knowledge, the Widening Gap in Translational Research and Future Challenges BioEssays · 2014
    20. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration Journal of Investigative Dermatology · 2012
    21. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    22. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    23. Inhibition of BMP Signaling Affects Growth and Differentiation in the Anagen Hair Follicle The EMBO Journal · 2000
    24. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999
    25. Role of Hair Papilla Cells in Induction and Regeneration Processes of Hair Follicles Wound Repair and Regeneration · 1998
    26. The Secret Life of the Hair Follicle Trends in genetics · 1992

    Related research 5

    1. Dysfunction of Hair Follicle Mesenchymal Progenitors Is Associated with Age-Related Hair Loss ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2019
    2. Protection Against Chemotherapy-Induced Alopecia: Targeting ATP-Binding Cassette Transporters in the Hair Follicle Trends in pharmacological sciences · 2013
    3. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    4. Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model Journal of Investigative Dermatology · 2010
    5. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001