The Impact of Skin Massage Frequency on the Intrafollicular Transport of Silica Nanoparticles: Validation of the Ratchet Effect on an Ex Vivo Porcine Skin Model

    November 2020 in “ European Journal of Pharmaceutics and Biopharmaceutics ”
    Loris Busch, Yasemin Keziban, Lars Dähne … Alexa Patzelt
    Studysummary This study found that low massage frequencies like 4.2 Hz enhance nanoparticle penetration into hair follicles more effectively than higher frequencies, indicating potential applications in therapeutic and cosmetic delivery.
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    Research cited in this study 18

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