Indole Glycosides from Calanthe Discolor with Proliferative Activity on Human Hair Follicle Dermal Papilla Cells

    April 2021 in “ Chemical & Pharmaceutical Bulletin ”
    Toshio Morikawa, Yoshiaki Manse, Fenglin Luo … Masayuki Yoshikawa
    Studysummary This study found that indole glycosides from Calanthe discolor Lindl. can significantly promote the proliferation of human hair follicle dermal papilla cells, potentially through upregulating specific growth factors.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jstage.jst.go.jp →
    Discuss this study in the Community →

    Research cited in this study 21

    1. Ent-Kaurane-Type Diterpenoids from Isodonis Herba Activate Human Hair Follicle Dermal Papilla Cells Proliferation via the Akt/GSK-3β/β-Catenin Transduction Pathway Journal of Natural Medicines · 2021
    2. Geranylated Coumarins From Thai Medicinal Plant Mammea Siamensis With Testosterone 5α-Reductase Inhibitory Activity Frontiers in Chemistry · 2020
    3. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    4. Flavonoid Silibinin Increases Hair-Inductive Property Via Akt and Wnt/β-Catenin Signaling Activation in 3-Dimensional Spheroid Cultured Human Dermal Papilla Cells Journal of Microbiology and Biotechnology · 2019
    5. Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth International Journal of Cosmetic Science · 2018
    6. Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex Evidence-based Complementary and Alternative Medicine · 2015
    7. Potential Targets in the Discovery of New Hair Growth Promoters for Androgenic Alopecia Expert Opinion on Therapeutic Targets · 2014
    8. The Human Hair: From Anatomy to Physiology International Journal of Dermatology · 2013
    9. Comparative GC-MS Based In Vitro Assays of 5α-Reductase Activity Using Rat Liver S9 Fraction Mass spectrometry letters · 2012
    10. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011
    11. Discovery of a Novel Hybrid from Finasteride and Epristeride as 5α-Reductase Inhibitor Bioorganic & Medicinal Chemistry Letters · 2010
    12. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010
    13. Human Type 3 5α-Reductase Is Expressed in Peripheral Tissues at Higher Levels Than Types 1 and 2 and Its Activity Is Potently Inhibited by Finasteride and Dutasteride Hormone Molecular Biology and Clinical Investigation · 2010
    14. Microencapsulated Human Hair Dermal Papilla Cells: A Substitute for Dermal Papilla? Archives of Dermatological Research · 2008
    15. The Hair Cycle Journal of Cell Science · 2006
    16. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    17. Finasteride and the Hair Cycle Journal of The American Academy of Dermatology · 2000
    18. Androgen-Dependent Beard Dermal Papilla Cells Secrete Autocrine Growth Factors in Response to Testosterone Unlike Scalp Cells ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    19. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    20. Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells Journal of Investigative Dermatology · 1996
    21. Hypertrichosis Due to Minoxidil British Journal of Dermatology · 1979

    Related research 7

    1. Possible Cellular Communication with Human Follicle Dermal Papilla Cells via Secretions from Human Hair Follicle Keratinocytes Journal of St. Marianna University · 2022
    2. A Model System to Analyze the Ability of Human Keratinocytes to Form Hair Follicles Experimental Dermatology · 2014
    3. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    4. Hair Follicle Reformation Induced by Dermal Papilla Cells from Human Scalp Skin Archives of Dermatological Research · 2006
    5. Study on Hair Follicle Formation Induced by Dermal Papilla Cells Chinese Journal of Reparative and Reconstructive Surgery · 2003
    6. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001
    7. Role of Hair Papilla Cells in Induction and Regeneration Processes of Hair Follicles Wound Repair and Regeneration · 1998