Immunogenetic and Metabolic Risk Factors in Male Androgenetic Alopecia: The Role of HLA-DRB1 Alleles and Vitamin D3 Deficiency

    December 2025 in “ Çukurova medical journal (Online)/Çukurova medical journal ”
    Tuğba Tehçi, Ümit Türsen
    Studysummary In this retrospective review, increased frequencies of certain HLA-DRB1 alleles and low vitamin D3 levels were observed in men with androgenetic alopecia, suggesting an association with immunogenetic factors and potential relevance for screening and treatment decisions.
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    Research cited in this study 24

    1. Genetic Variants and Lifestyle Factors in Androgenetic Alopecia Patients: A Case-Control Study of Single Nucleotide Polymorphisms and Their Contribution to Baldness Risk Nutrients · 2025
    2. Is Early-Onset Androgenetic Alopecia Associated With Metabolic Syndrome? A Descriptive Cross-Sectional Study International Journal of Trichology · 2025
    3. Serum 25 Hydroxyvitamin D in Non-Scarring Alopecia: A Systematic Review and Meta-Analysis Journal of Cosmetic Dermatology · 2023
    4. The Association of Serum Adipokines, Insulin Resistance and Vitamin D Status in Male Patients with Androgenetic Alopecia Clinical, Cosmetic and Investigational Dermatology · 2023
    5. The Psychological Consequences of Androgenetic Alopecia: A Systematic Review Journal of Cosmetic Dermatology · 2022
    6. Systematic Review and Meta-Analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia Acta dermato-venereologica · 2021
    7. Prevalence of Low Serum Vitamin D Levels in Patients Presenting With Androgenetic Alopecia: A Review Cureus · 2021
    8. Implications of Cigarette Smoking on Early-Onset Androgenetic Alopecia: A Cross-Sectional Study Journal of Cosmetic Dermatology · 2020
    9. Evaluation of the Relationship Between Androgenetic Alopecia and Blood Groups and Rhesus Factor International Journal of Clinical Practice · 2020
    10. Study of Serum Vitamin D Levels in Men with Premature Androgenetic Alopecia International Journal of Dermatology · 2020
    11. Association of Androgenetic Alopecia with Metabolic Syndrome: A Case-Control Study on 100 Patients in a Tertiary Care Hospital in South India Indian Journal of Endocrinology and Metabolism · 2018
    12. Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways British Journal of Dermatology · 2017
    13. A Comparison of the Hormonal Profile of Early Androgenetic Alopecia in Men With the Phenotypic Equivalent of Polycystic Ovarian Syndrome in Women JAMA Dermatology · 2016
    14. Metabolic Syndrome in Androgenic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2016
    15. Platelet-Rich Plasma in Dermatology: Boon or Bane? Indian Journal of Dermatology, Venereology and Leprology · 2014
    16. Association of Androgenetic Alopecia With Mortality From Diabetes Mellitus and Heart Disease JAMA Dermatology · 2013
    17. The Annual Changes of Clinical Manifestation of Androgenetic Alopecia Clinic in Korean Males and Females: An Outpatient-Based Study Annals of Dermatology · 2013
    18. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men Journal der Deutschen Dermatologischen Gesellschaft · 2011
    19. The Effects of Autologous Platelet-Rich Plasma and Various Growth Factors on Non-Transplanted Miniaturized Hair Hair transplant forum international · 2009
    20. Obesity and Low-Grade Inflammation Among Young Finnish Men With Early-Onset Alopecia Dermatology · 2007
    21. Family History and Risk of Hair Loss Dermatology · 2004
    22. Early Onset of Androgenetic Alopecia Associated With Early Severe Coronary Heart Disease: A Population-Based, Case-Control Study European journal of cardiovascular prevention & rehabilitation · 2001
    23. Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp Journal of Endocrinology · 1998
    24. Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia Dermatologic Clinics · 1996