3 citations
,
January 2023 in “SAGE Open Medical Case Reports” This case study reports significant hair regrowth in a 61-year-old woman with alopecia universalis after she was treated with hydroxychloroquine for accompanying granuloma annulare.
1 citations
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May 2022 in “Frontiers in Psychiatry” In this case study, a 33-year-old female with neuropsychiatric systemic lupus erythematosus experienced hair regrowth with no further loss after receiving a combination of systemic and local treatments.
3 citations
,
September 2021 in “Journal of Nepal Medical Association” This case report describes successful treatment of alopecia universalis associated with severe hyperthyroidism using azathioprine and hydroxychloroquine after poor response to oral steroid therapy.
August 2021 in “Case Reports” This report describes a case where a woman with frontal fibrosing alopecia initially presented with symptoms resembling rosacea, but further investigation led to a diagnosis of FFA, resulting in a treatment change to oral finasteride and hydroxychloroquine.
4 citations
,
January 2021 in “Postępy Dermatologii i Alergologii” This study found that hydroxychloroquine significantly reduced disease activity in women with frontal fibrosing alopecia and lichen planopilaris, particularly benefitting patients after 12 months of treatment.
4 citations
,
December 2020 This case report describes a woman with frontal fibrosing alopecia who did not improve with hydroxychloroquine and topical minoxidil but achieved clinical stabilization with methotrexate monotherapy.
9 citations
,
July 2020 in “Journal of Dermatology” This study found that diffuse and pseudo-fringe sign patterns are common in Asian patients with frontal fibrosing alopecia, and that treatments combining antiandrogens or antimalarials with topical therapy are effective.
12 citations
,
July 2020 in “Actas Dermo-Sifiliográficas” This study found that facial papules and rosacea in patients with frontal fibrosing alopecia were linked to a greater need for oral treatment, with most cases involving postmenopausal women.
3 citations
,
December 2019 in “Lupus” In this report, researchers describe a case of scalp discoid lupus erythematosus unresponsive to topical treatments, where hydroxychloroquine administered at 200 mg/day led to complete resolution of skin lesions in five months.
8 citations
,
October 2019 in “International Journal of Dermatology” This study examined 56 Thai patients with frontal fibrosing alopecia, finding frontotemporal hairline recession and eyebrow loss were common, and reported better disease stabilization with combination treatments of topical corticosteroids with hydroxychloroquine or finasteride.
61 citations
,
January 2019 in “American Journal of Clinical Dermatology” This review discusses the potential causes and treatments for frontal fibrosing alopecia but reports no new clinical findings, highlighting the need for further research to understand its pathogenesis and develop validated treatments.
23 citations
,
November 2018 in “Journal of the European Academy of Dermatology and Venereology” This study observed that frontal fibrosing alopecia is increasingly diagnosed in Italian Caucasian females, often showing premenopausal onset and eyebrow alopecia as an early sign.
48 citations
,
November 2018 in “Journal of dermatological treatment” In a study reviewing 291 patients with lichen planopilaris, findings revealed that women were more commonly affected than men, cyclosporine and methotrexate were most effective in achieving remission, and 5-alpha reductase inhibitors and systemic retinoids were particularly beneficial for frontal fibrosing alopecia.
19 citations
,
August 2018 in “International Journal of Dermatology” In this study, lupus panniculitis of the scalp was associated with a high incidence of recurrence and progression to systemic lupus erythematosus, despite various treatments showing complete response within weeks.
17 citations
,
March 2018 in “Pediatric dermatology” This study suggests that hydroxychloroquine may benefit some children with alopecia areata, as five out of nine patients showed improvement, although side effects like gastrointestinal intolerance and headache were noted.
25 citations
,
December 2017 in “Facial Plastic Surgery” This study observed that combining high-potency steroids with pimecrolimus might effectively stabilize hairline recession in frontal fibrosing alopecia patients.
19 citations
,
July 2017 in “Clinical and experimental dermatology” This study provides one of the first descriptions of the demographic, clinical, and therapeutic characteristics of lichen planopilaris in Chilean adults, reporting that treatment usually reduced or halted disease progression.
41 citations
,
July 2017 in “Journal of The American Academy of Dermatology” This study observed that frontal fibrosing alopecia also occurs in men, with clinical features and areas of involvement similar to those seen in women, but often affecting sideburns and facial hair.
8 citations
,
January 2017 in “Acta Dermato Venereologica” Thorough clinical examination is crucial for diagnosing unusual alopecia.
17 citations
,
June 2016 in “Australasian Journal of Dermatology” In this case report, a 46-year-old woman with familial frontal fibrosis alopecia experienced initial stabilization of hair loss with dutasteride and minoxidil, but artificial hair transplantation led to implant folliculitis, requiring removal of the fibers.
12 citations
,
January 2016 in “Skin Appendage Disorders” This study reports an association between frontal fibrosing alopecia and lupus erythematosus, noting progressive alopecia in the frontotemporal hairline despite treatment with hydroxychloroquine.
47 citations
,
June 2014 in “Journal of Dermatological Treatment” This retrospective review found that while intralesional corticosteroids provided symptomatic improvement for lichen planopilaris, hydroxychloroquine with topical corticosteroids led to higher remission rates but did not result in visible hair regrowth.
102 citations
,
April 2014 in “International Journal of Dermatology” This study found that early intervention and treatment with intralesional triamcinolone acetonide may stabilize hairline recession in patients with frontal fibrosing alopecia, although further research is needed for definitive treatment guidelines.
339 citations
,
February 2014 in “Journal of The American Academy of Dermatology” This study found that eyelash loss, facial papules, and body hair involvement were linked to severe frontal fibrosing alopecia, and antiandrogens were the most effective treatment.
11 citations
,
May 2013 in “Journal of the American Academy of Dermatology” Hydroxychloroquine helped two people regrow hair lost from alopecia totalis.
117 citations
,
March 2013 in “Journal of the European Academy of Dermatology and Venereology” This study reported that while no effective treatment exists for frontal fibrosing alopecia, oral 5-alpha-reductase inhibitors showed the most promise, inducing a good clinical response in 45% of patients.
98 citations
,
January 2013 in “Journal of The American Academy of Dermatology” This study reported that while various treatments for frontal fibrosing alopecia showed limited effectiveness, dutasteride most effectively stabilized the condition among patients at Duke University.
166 citations
,
April 2012 in “Journal of The American Academy of Dermatology” This study reviewed clinical data from 60 patients with frontal fibrosing alopecia and found increasing prevalence and generally poor response to treatment, with the cause remaining unclear.
34 citations
,
December 2011 in “The Journal of Dermatology” This study describes a distinct variant of lupus panniculitis in East Asians, characterized by reversible, linear alopecia along Blaschko’s lines on the scalp, without systemic lupus erythematosus associations.
159 citations
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August 2010 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, hydroxychloroquine significantly reduced signs and symptoms of frontal fibrosing alopecia after 6 months of treatment, with maximal benefits observed within the first 6 months.
19 citations
,
May 2009 in “Pediatric Dermatology” This case report describes a 5-year-old girl with childhood discoid lupus erythematosus, where treatment led to reversal of scarring alopecia and hair regrowth.
43 citations
,
March 2009 in “Archives of dermatology” No treatment showed clear superiority for lichen planopilaris.
155 citations
,
September 2008 in “British journal of dermatology/British journal of dermatology, Supplement” This study observed that frontal fibrosing alopecia predominantly affects postmenopausal women, can be associated with lichen planus, and may lead to progressive hairline recession, though this progression is not consistent in all cases.
28 citations
,
July 2002 in “Australasian Journal of Dermatology” This case report describes a 27-year-old woman with lupus erythematosus whose biopsy findings indicated that lupus panniculitis can mimic alopecia areata, leading to temporary hair loss.
