This review discusses the association between scarring alopecia and inflammatory processes in common acquired bullous disorders of the scalp, and reports no new clinical findings.
11 citations
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June 2017 in “Mathematical Medicine and Biology A Journal of the IMA”
This mathematical model of alopecia areata illustrates how inflammatory autoimmune responses interrupt the anagen phase of hair growth, and may help evaluate treatments and identify new therapeutic targets.
July 2022 in “International Journal of Applied Pharmaceutics”
This research explored the use of machine learning and deep learning methods to accurately identify alopecia areata in humans by analyzing facial images and demonstrated the potential of these techniques for medical, security, and commercial applications.
In this review, the authors detailed the clinical, trichoscopic, and histopathological features of hairdisorders linked to autoimmune diseases, highlighting the role of dermatologists in identifying possible underlying autoimmune conditions in patients presenting with hair loss.
This review discusses various hairdisorders associated with autoimmune connective tissue diseases, particularly lupus erythematosus, and highlights diagnostic approaches but reports no new clinical results.
An arthritis drug, Rinvoq, restores hair in some alopecia areata patients but is not effective for androgenetic alopecia. It is used for autoimmune-related skin disorders, but its high cost and lack of insurance coverage are issues.
The user experienced significant hair thinning despite using finasteride and minoxidil, leading to concerns about whether it's a temporary shed or a more serious issue. They plan to start using RU58841 and are advised to consult a doctor to rule out other causes like autoimmunedisorders.
Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.
A user is experiencing rapid hair loss and has been diagnosed with telogen effluvium by multiple dermatologists, but doubts the diagnosis due to the severity and speed of the hair loss. They are considering various treatments like spironolactone, estradiol, and possibly finasteride, while also exploring the possibility of hormonal imbalances or autoimmune issues.
The conversation suggests that people should consult a dermatologist to understand their type of hair loss before starting treatments like finasteride or dutasteride, especially if they have autoimmune issues or low DHT. Some participants believe in starting treatment like finasteride immediately if hair loss is due to DHT, while others recommend ruling out other causes and considering minoxidil first, especially for younger individuals.
What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata?Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.
Is scalp micropigmentation safe?Providers describe scalp micropigmentation as low-risk when a trained practitioner uses sterile single-use equipment, but that is a provider claim rather than a regulatory finding: pigment allergy, infection and colour change are documented risks of cosmetic tattooing.