Frontal Fibrosing Alopecia Coexisting With Lupus Erythematosus: Poor Response To Hydroxychloroquine

    January 2016 in “ Skin Appendage Disorders
    Letícia Arsie Contin, Elisa Raquel Martins da Costa Marques, Leandro Fonseca Noriega
    TLDR Hydroxychloroquine is ineffective for treating frontal fibrosing alopecia with lupus erythematosus.
    The document reported on 4 female patients with coexisting frontal fibrosing alopecia (FFA) and lupus erythematosus (LE), who showed poor response to hydroxychloroquine treatment. Despite treatment, all patients experienced progressive alopecia in the frontotemporal hairline. The study suggested a common immune background for FFA and LE, explaining their association, and indicated that hydroxychloroquine, effective for LE, did not halt FFA progression in these cases.
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