Lichen Planopilaris in a Latin American (Chilean) Population: Demographics, Clinical Profile, and Treatment Experience

    July 2017 in “ Clinical and experimental dermatology ”
    Francisco Mardones, Jerry Shapiro
    TLDR Men with lichen planopilaris had earlier onset than women, and treatment usually improved the condition.
    The study retrospectively reviewed 103 Chilean adults diagnosed with lichen planopilaris (LPP), including 67 women (mean age 54.1 years) and 36 men (mean age 39.1 years). It found that men with classic LPP (CLPP) had an earlier onset than women, and common symptoms included scalp dysaesthesia, erythema, and peripilar hyperkeratosis. Most patients with CLPP had cicatricial patches, primarily in the vertex area, while those with frontal fibrosing alopecia (FFA) exhibited band-like scarring in the frontal and temporal hairlines. Associated morbidities included hypothyroidism, dyslipidaemia, hypertension, and depression. Treatment typically required a combination of topical and systemic medications, which generally halted or improved the condition. This study highlighted the need for larger multicentre international research on LPP in diverse populations.
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