Therapeutic Approach for Hair Growth and Regeneration Using Bioactive Formulation Containing Mesenchymal Stromal Cell-Derived Conditioned Medium

The research paper discusses a study conducted on 40 healthy Indian volunteers (10 males and 30 females) aged 18 to 65 years, testing the efficacy of a hair growth serum, Trichosera®, developed using conditioned media (CM) from adult human bone marrow-derived mesenchymal stromal cells (BM-MSCs). The CM contains growth factors and cytokines that promote hair growth. The study lasted for 24 weeks and showed that the use of MSC derived CM significantly increased human hair regrowth (18.66%) and hair density (11.54%), while reducing hair fall rate (48.65%). The serum was also found to be safe, with no significant adverse reactions. The study suggests that Trichosera® could be a promising alternative to current therapies for androgenetic alopecia (AGA). However, further studies with larger sample sizes are recommended.