Frontal Fibrosing Alopecia and the Role of Cosmeceuticals in Its Pathogenesis

    August 2025 in “ Cosmetics ”
    Kristijan Harak, Lucija Tomić Krsnik, Marija Vukojević … Zrinka Bukvić Mokoš
    Studysummary This review discusses the possible link between cosmeceuticals and frontal fibrosing alopecia but reports no conclusive findings; the authors stress further research on environmental triggers is needed.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 55

    1. FFA Patient Profile Analysis Based on Authors' Observations and Literature Review—An Original Survey Journal of Clinical Medicine · 2025
    2. Frontal Fibrosing Alopecia in Men: A Review of the Literature 2025
    3. The Frontal Fibrosing Alopecia Treatment Dilemma Journal of clinical medicine · 2024
    4. Sensitization to Ethylhexyl Salicylate: Another Piece of the Frontal Fibrosing Alopecia Puzzle Contact dermatitis · 2023
    5. Case Series of Frontal Fibrosing Alopecia and Fibrosing Alopecia in a Pattern Distribution: Is There a Familial Correlation? Skin Appendage Disorders · 2023
    6. Frontal Fibrosing Alopecia: A Review of Disease Pathogenesis Frontiers in Medicine · 2022
    7. The Association Between Frontal Fibrosing Alopecia, Sunscreen, and Moisturizers: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2022
    8. Frontal Fibrosing Alopecia: A Review and Practical Guide for Clinicians Annals of Agricultural and Environmental Medicine · 2021
    9. Use of Facial Care Products and Frontal Fibrosing Alopecia: Coincidence or True Association? The Journal of Dermatology · 2021
    10. Familial Frontal Fibrosing Alopecia Sultan Qaboos University medical journal · 2021
    11. Frontal Fibrosing Alopecia: A Review Journal of Clinical Medicine · 2021
    12. Medical Comorbidities and Sex Distribution Among Patients With Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective Cohort Study Journal of the American Academy of Dermatology · 2020
    13. Clinical Characteristics, Trichoscopy, Histopathology, and Treatment Outcomes of Frontal Fibrosing Alopecia in an Asian Population: A Retro-Prospective Cohort Study Journal of Dermatology · 2020
    14. Frontal Fibrosing Alopecia: An Example of Disrupted Aryl Hydrocarbon Receptor-Mediated Immunological Homeostasis in the Skin? Clinical, cosmetic and investigational dermatology · 2020
    15. Patch Testing and Contact Allergen Avoidance in Patients with Lichen Planopilaris and/or Frontal Fibrosing Alopecia: A Cohort Study Journal of the American Academy of Dermatology · 2020
    16. A Novel Atypical Presentation of Frontal Fibrosing Alopecia Involving the Frontoparietal Scalp Skin appendage disorders · 2020
    17. Frontal Fibrosing Alopecia in Asians: A Retrospective Clinical Study International Journal of Dermatology · 2019
    18. Frontal Fibrosing Alopecia: Demographic and Clinical Characteristics of 490 Cases JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    19. Genome-Wide Association Study in Frontal Fibrosing Alopecia Identifies Four Susceptibility Loci Including HLA-B*07:02 Nature Communications · 2019
    20. Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study Skin appendage disorders · 2019
    21. Facial and Extrafacial Lesions in an Ethnically Diverse Series of 91 Patients with Frontal Fibrosing Alopecia Followed at a Single Center Dermatology · 2018
    22. The Value of Dermoscopy in Diagnosing Eyebrow Loss in Patients with Alopecia Areata and Frontal Fibrosing Alopecia Journal of the European Academy of Dermatology and Venereology · 2018
    23. Differential Expression of mTOR Signaling Pathway Proteins in Lichen Planopilaris and Frontal Fibrosing Alopecia Acta histochemica · 2018
    24. Lichen Planopilaris in the Context of Hair Sunscreen Spray Skin appendage disorders · 2018
    25. Frontal Fibrosing Alopecia: Regrowth Following Cessation of Sunscreen on the Forehead Australasian Journal of Dermatology · 2018
    26. Updated Diagnostic Criteria for Frontal Fibrosing Alopecia Journal of The American Academy of Dermatology · 2017
    27. The Increasing Incidence of Frontal Fibrosing Alopecia: In Search of Triggering Factors Journal of the European Academy of Dermatology and Venereology · 2017
    28. Unusual Patterns of Presentation of Frontal Fibrosing Alopecia: A Clinical and Trichoscopic Analysis of 98 Patients Journal of The American Academy of Dermatology · 2017
    29. Frontal Fibrosing Alopecia: Clinical and Prognostic Classification JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2017
    30. PPAR-γ Agonists and Their Role in Primary Cicatricial Alopecia PPAR Research · 2017
    31. DHEA and Frontal Fibrosing Alopecia: Molecular and Physiopathological Mechanisms Anais Brasileiros de Dermatologia · 2016
    32. Frontal Fibrosing Alopecia: Reflections and Hypotheses on Etiology and Pathogenesis Experimental dermatology · 2016
    33. Isolated Eyebrow Loss in Frontal Fibrosing Alopecia: Relevance of Early Diagnosis and Treatment British journal of dermatology/British journal of dermatology, Supplement · 2016
    34. Trichoscopic Features of Frontal Fibrosing Alopecia: Results in 249 Patients Journal of The American Academy of Dermatology · 2015
    35. Frontal Fibrosing Alopecia: A Multicenter Review of 355 Patients Journal of The American Academy of Dermatology · 2014
    36. The Human Hair: From Anatomy to Physiology International Journal of Dermatology · 2013
    37. Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche The Journal of Pathology · 2013
    38. Frontal Fibrosing Alopecia: A Retrospective Review of 19 Patients Seen at Duke University Journal of The American Academy of Dermatology · 2013
    39. Perifollicular Erythema as a Trichoscopy Sign of Progression in Frontal Fibrosing Alopecia International journal of trichology · 2013
    40. Estrogen Leads to Reversible Hair Cycle Retardation Through Inducing Premature Catagen and Maintaining Telogen PLOS ONE · 2012
    41. Frontal Fibrosing Alopecia: A Review of 60 Cases Journal of The American Academy of Dermatology · 2012
    42. Hair and Scalp Dermatoscopy Journal of The American Academy of Dermatology · 2012
    43. Trichoscopy Update 2011 Journal of Dermatological Case Reports · 2011
    44. Lonely Hair Archives of Dermatology · 2011
    45. Frontal Fibrosing Alopecia: A Clinical Review of 36 Patients British journal of dermatology/British journal of dermatology, Supplement · 2010
    46. Expression of Snail1 in the Fibrotic Dermis of Postmenopausal Frontal Fibrosing Alopecia: Possible Involvement of an Epithelial-Mesenchymal Transition and a Review of Japanese Patients British Journal of Dermatology · 2010
    47. Frontal Fibrosing Alopecia: Role of Dermoscopy in Differential Diagnosis Case reports in dermatology · 2010
    48. Frontal Fibrosing Alopecia: Clinical Presentations and Prognosis British journal of dermatology/British journal of dermatology, Supplement · 2008
    49. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007
    50. Frontal Fibrosing Alopecia: Diagnostic and Therapeutic Assessment Actas Dermo-Sifiliográficas · 2007
    51. Frontal Fibrosing Alopecia: A Survey in 16 Patients Journal of the European Academy of Dermatology and Venereology · 2005
    52. Frontal Fibrosing Alopecia Developing After Hair Transplantation for Androgenetic Alopecia International Journal of Dermatology · 2005
    53. Postmenopausal Frontal Fibrosing Alopecia: A Frontal Variant of Lichen Planopilaris Journal of the American Academy of Dermatology · 1997
    54. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996
    55. Postmenopausal Frontal Fibrosing Alopecia Archives of Dermatology · 1994