Sensitization to Ethylhexyl Salicylate: Another Piece of the Frontal Fibrosing Alopecia Puzzle

The document presents a study investigating the potential link between Frontal Fibrosing Alopecia (FFA) and sensitization to ethylhexyl salicylate (EHS), a common ingredient in sunscreens and cosmetics. The study involved 33 FFA patients, with 27.3% showing positive reactions to EHS. The study also reviewed 12 cases of EHS sensitization and evaluated 518 dermo-cosmetic products, finding EHS in 14.7% of them. The authors suggest that EHS could be a potential allergen contributing to FFA and recommend further investigation. They also speculate that high exposure to sunscreens could lead to a higher risk of contact sensitization to their ingredients, but whether this can impact the pathogenesis of FFA remains speculative.