Camellia Japonica Seed Extract Promotes Hair Growth by Preventing Dermal Papilla Cell Senescence and Activating Hair Follicle Stem Cells

    July 2025 in “ Biotechnology and Bioprocess Engineering ”
    Min Jung Hong, Su Na Kim, Soyoung Shin, Jaeyoung Ko, S PARK, Seung Hun Kim, Gi Baeg Nam, Won Seok Park, Byung Cheol Park, Hyoung-June Kim
    Image of study
    TLDR Camellia japonica seed extract helps hair grow by activating hair follicles and preventing cell aging.
    The study found that Camellia japonica seed extract (CJSE) promotes hair growth by preventing dermal papilla cell senescence and activating hair follicle stem cells. CJSE inhibited premature senescence in dermal papilla cells by suppressing p16 expression and increasing Rb phosphorylation, while also enhancing hair follicle stem cell activity by reducing p21 expression. A clinical trial with 47 participants showed that a topical scalp tonic containing 2% CJSE significantly increased hair density over 24 weeks. These results suggest that CJSE could be an effective treatment for androgenic or senescent alopecia by maintaining the anagen phase of hair follicles and enhancing hair growth.
    Discuss this study in the Community →

    Research cited in this study

    15 / 15 results

    Related Community Posts Join

    6 / 9 results

      community Is 0.1%w/v topical fin overkill if taking oral 0.5mg fin?

      in Finasteride/Dutasteride  2 upvotes 1 week ago
      The conversation discusses whether using 0.1% topical finasteride alongside 0.5 mg oral finasteride is excessive, with suggestions to choose either oral or topical treatment. The user also uses 5% minoxidil and mentions concerns about alcohol-based solutions due to seborrheic dermatitis.

      community Alternatives to Minox for pet safety

      in Minoxidil  2 upvotes 1 month ago
      The conversation discusses alternatives to minoxidil for beard growth, focusing on a product called Neofollics Beard Growth Serum, which claims to be effective without using minoxidil. Concerns are raised about its ingredients and effectiveness, especially considering pet safety.

      community Why is no one talking about redensyl?

      in Question  53 upvotes 6 years ago
      Exploring the effectiveness of redensyl, a hair loss treatment, compared to minoxidil and finasteride. People shared experiences using redensyl and products containing it, such as The Ordinary Hair Serum.

    Related Research

    7 / 7 results