Identifying the Active Components and Mechanisms of Persicae Semen in Treating Androgenetic Alopecia: Insights from Network Pharmacology and Experimental Evaluations

April 2025 in “ Journal of Ethnopharmacology ”

Xiaojuan Li, Xiaoli Liu, Bin Li, Ziyi Liu, Shiqi Guo, Sha Xiong, Ting Xiao, Siwen Jiao, Yu Chen, Yuehong Xu

Persicae Semen androgenetic alopecia UPLC-Q-TOF-MS network pharmacology molecular docking amygdalin Wnt/β-catenin pathway VEGF pathway androgen receptor 5α-reductase TR AGA Am Wnt pathway vascular endothelial growth factor pathway AR

Studysummary This study elucidated the multi-component and multi-target mechanisms by which TR and Am may provide therapeutic benefits for treating androgenetic alopecia.

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