Expression of the Heat Shock Protein-27 in the Adult Human Scalp Skin and Hair Follicle: Hair Cycle–Dependent Changes

April 2006 in “ Journal of the American Academy of Dermatology ”

Mohamed A. Adly, Hanan Assaf, Mahmoud R. Hussein

heat shock protein-27 HSP-27 hair follicle hair cycle scalp skin hair growth follicle health molecular mechanisms hair cycle regulation

TLDR Heat shock protein 27 is more present in the active growth phase of human scalp hair follicles.

The study investigated the expression of heat shock protein-27 (HSP-27) in adult human scalp skin and hair follicles, focusing on changes dependent on the hair cycle. The findings indicated that HSP-27 expression varied significantly throughout different phases of the hair cycle, suggesting a potential role in hair growth and follicle health. This research provided insights into the molecular mechanisms underlying hair cycle regulation and highlighted the importance of HSP-27 in maintaining hair follicle function.

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