Modern Approaches to Treatment of Alopecia X in Dogs: Review of Research

    A. Kochetkova, Anna Fomina, Tatyana Derezina
    Studysummary This source reviews existing studies on treating canine noninflammatory alopecia, identifying microneedling and oral administration of certain drugs as optimal methods with fewer side effects, while noting that other treatments like mitotane and minoxidil cause serious side effects, limiting their future use.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 35

    1. What's New in Therapy for Male Androgenetic Alopecia? American Journal of Clinical Dermatology · 2022
    2. A Comprehensive Review of Microneedling as a Potential Treatment Option for Androgenetic Alopecia Aesthetic Plastic Surgery · 2022
    3. Microneedling and Its Use in Hair Loss Disorders: A Systematic Review Dermatology and therapy · 2021
    4. Topical Minoxidil Exposures and Toxicoses in Dogs and Cats: 211 Cases (2001–2019) ˜The œJournal of the American Animal Hospital Association/Journal of the American Animal Hospital Association · 2021
    5. Minoxidil: A Comprehensive Review Journal of Dermatological Treatment · 2021
    6. Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients Journal of The American Academy of Dermatology · 2021
    7. Systematic Review of Platelet-Rich Plasma in Treating Alopecia: Focusing on Efficacy, Safety, and Therapeutic Durability Dermatologic Therapy · 2021
    8. Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial Journal of The American Academy of Dermatology · 2019
    9. Platelet-Rich Plasma for Treating Androgenic Alopecia: A Systematic Review Aesthetic Plastic Surgery · 2019
    10. Case Series of Oral Minoxidil for Androgenetic and Traction Alopecia: Tolerability and the Five C’s of Oral Therapy Dermatologic Therapy · 2018
    11. Novel Insights Into the Pathways Regulating the Canine Hair Cycle and Their Deregulation in Alopecia X PLOS ONE · 2017
    12. A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia International Journal of Trichology · 2017
    13. Repeated Microneedle Stimulation Induces Enhanced Hair Growth in a Murine Model Annals of Dermatology · 2016
    14. Microneedling as a Successful Treatment for Alopecia X in Two Pomeranian Siblings Veterinary Dermatology · 2015
    15. Deslorelin for the Treatment of Hair Cycle Arrest in Intact Male Dogs Veterinary dermatology · 2014
    16. Treatment of Alopecia X with Medroxyprogesterone Acetate Veterinary dermatology · 2013
    17. Canine Noninflammatory Alopecia: A Comprehensive Evaluation of Common and Distinguishing Histological Characteristics Veterinary Dermatology · 2012
    18. From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber Journal of Investigative Dermatology · 2009
    19. Estrogen Receptor Antagonist and Hair Regrowth in Dogs with Hair Cycle Arrest (Alopecia X) Veterinary dermatology · 2007
    20. An Overview on Congenital Alopecia in Domestic Animals Veterinary dermatology · 2006
    21. The Use of Trilostane for the Treatment of Alopecia X in Alaskan Malamutes ˜The œJournal of the American Animal Hospital Association/Journal of the American Animal Hospital Association · 2005
    22. Growth Hormone-Responsive Alopecia in Dogs Journal of the American Veterinary Medical Association · 2005
    23. Treatment of Canine Alopecia X with Trilostane Veterinary Dermatology · 2004
    24. Adrenal Steroid Hormone Concentrations in Dogs with Hair Cycle Arrest (Alopecia X) Before and During Treatment with Melatonin and Mitotane Veterinary dermatology · 2004
    25. Hypertrichosis in Females Applying Minoxidil Topical Solution and in Normal Controls Journal of The European Academy of Dermatology and Venereology · 2003
    26. The Potential Role of Minoxidil in the Hair Transplantation Setting Dermatologic Surgery · 2002
    27. Exogen, Shedding Phase of the Hair Growth Cycle: Characterization of a Mouse Model Journal of Investigative Dermatology · 2002
    28. Trilostane Treatment of 78 Dogs With Pituitary-Dependent Hyperadrenocorticism Veterinary record/˜The œveterinary record · 2002
    29. Results of Clinical Examinations, Laboratory Tests, and Ultrasonography in Dogs with Pituitary-Dependent Hyperadrenocorticism Treated with Trilostane American journal of veterinary research · 2002
    30. Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment Journal of The American Academy of Dermatology · 2002
    31. The Pharmacologic Basis of the Cardiovascular Toxicity of Minoxidil in the Dog Toxicologic Pathology · 1995
    32. Natural History of Androgenetic Alopecia Clinical and Experimental Dermatology · 1990
    33. The History of the Development of Minoxidil Clinics in Dermatology · 1988
    34. Contact Dermatitis to Minoxidil Contact Dermatitis · 1985
    35. Minoxidil: A Review of Its Pharmacological Properties and Therapeutic Use Drugs · 1981