Topical Minoxidil Exposures and Toxicoses in Dogs and Cats: 211 Cases (2001–2019)

    August 2021 in “ ˜The œJournal of the American Animal Hospital Association/Journal of the American Animal Hospital Association ”
    Kathy Tater, Sharon M. Gwaltney‐Brant, Tina Wismer
    Studysummary This study observed that accidental topical minoxidil exposure can cause toxicosis in dogs and cats, leading to moderate or major illness, and even death in some cats.
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    Research cited in this study 14

    1. Successful Management of Minoxidil Toxicosis in a Dog Javma-journal of The American Veterinary Medical Association · 2018
    2. Microneedling as a Successful Treatment for Alopecia X in Two Pomeranian Siblings Veterinary Dermatology · 2015
    3. Cardiovascular Effects of Ingesting Topical Minoxidil in Pediatric Patients Pediatric emergency care · 2014
    4. Morphea-Like Lesion Following Topical Endectocide Application in a Cat Veterinary dermatology · 2012
    5. Topical Use of Minoxidil in Children and Systemic Side Effects Dermatology · 2007
    6. Minoxidil: An Underused Vasodilator for Resistant or Severe Hypertension Journal of Clinical Hypertension · 2004
    7. Topically Applied Minoxidil May Cause Fetal Malformation: A Case Report Teratology · 2003
    8. A Case of Acute Myocardial Infarction Associated with Topical Use of Minoxidil for Treatment of Baldness Japanese Heart Journal · 2000
    9. The Effect of Topical Minoxidil Treatment on Hair Follicular Growth of Neonatal Hairless Descendants of Mexican Hairless Dogs Veterinary Dermatology · 1997
    10. The Pharmacologic Basis of the Cardiovascular Toxicity of Minoxidil in the Dog Toxicologic Pathology · 1995
    11. Topical Minoxidil: Cardiac Effects in Bald Men British Journal of Clinical Pharmacology · 1988
    12. Topical Minoxidil Reduces Blood Pressure Journal of The American Academy of Dermatology · 1985
    13. Pharmacology and Pharmacokinetics of Minoxidil Journal of Cardiovascular Pharmacology · 1980
    14. Metabolism of Minoxidil, a New Hypotensive Agent: Biotransformation Following Oral Administration to Rats, Dogs, and Monkeys Journal of Pharmaceutical Sciences · 1975

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    2. Scalp Psoriasiform Contact Dermatitis with Acute Telogen Effluvium Due to Topical Minoxidil Treatment Skin appendage disorders · 2015