Morphea-Like Lesion Following Topical Endectocide Application in a Cat
March 2012
in “
Veterinary dermatology
”
New to Minoxidil? There is a guide in the encyclopedia. Read the guide → Studysummary This case report describes a potential drug-induced localized scleroderma in a Persian cat following the application of a 'spot-on' treatment. Our plain-language summary of this paper — not a Tressless recommendation.
A 3-year-old male Persian cat developed a localized morphea-like scleroderma lesion after the topical application of a solution containing praziquantel and emodepside. The lesion, characterized by a nonpruritic, well-demarcated alopecic plaque at the application site, showed histological signs of fibrosing dermatitis. Systemic treatment with pentoxifylline was ineffective, but topical minoxidil 5% led to complete hair regrowth and lesion resolution within 60 days. Although the relationship between the lesion and the topical solution could not be definitively proven, it was classified as a 'possible' adverse drug reaction according to the Naranjo scale. This case may represent the first documented sclerodermoid reaction to these substances in veterinary medicine and is the second report of a morphea-like lesion in a cat.
