Successful Management of Minoxidil Toxicosis in a Dog

    January 2018 in “ Javma-journal of The American Veterinary Medical Association ”
    Tyler J. M. Jordan, Page E. Yaxley, Christine A. Culler, Anusha Balakrishnan
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    TLDR A dog fully recovered from minoxidil poisoning after receiving treatment.
    In 2018, a 2-year-old female mixed-breed dog weighing 5.8 kg was successfully treated for minoxidil toxicosis after ingesting 5% minoxidil foam. The dog exhibited symptoms including vomiting, lethargy, tachycardia, and hypotension. Treatment involved a constant rate infusion of dopamine and esmolol hydrochloride, as well as an intravenous lipid emulsion (IVLE) and antiemetic medications. The dog's clinical signs resolved, and it made a full recovery four days post-admission. This case was the first reported successful clinical management of accidental minoxidil toxicosis in a dog, with the treatments administered contributing to the positive outcome, although the exact impact of each treatment was not determined. Financial constraints prevented more comprehensive diagnostic testing. The case underscores the need for veterinary awareness of minoxidil's toxic effects and the potential need for specialty care in such cases.
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