Minoxidil Overdose: Severe Hypotension and Tachycardia After Ingestion

    April 1993 in “ Chest ”
    Andrew M. MacMillan, F.J. Warshawski, Richard Steinberg
    Image of study
    TLDR Man drank minoxidil, caused low blood pressure and fast heartbeat, treatment helped but led to heart damage.
    A man ingested 60 ml of 2 percent topical minoxidil solution, resulting in severe hypotension and tachycardia. He was treated with intravenously administered crystalloid solution, dopamine, and phenylephrine infusion, resulting in a partial hemodynamic improvement and resolution of hypotension. The patient suffered a non-Q-wave myocardial infarction as a result of the ingestion. Minoxidil is originally used as an antihypertensive agent and is now approved for the treatment of male pattern baldness. The toxicity of this increasingly common preparation is profound.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community i got more results 1 month 5 mg oral minoxidil and 1 mg dutasteride then i did 6 months on finasteride and topical minoxidil

      in Finasteride/Dutasteride  49 upvotes 1 year ago
      A user reported better hair regrowth with 5 mg oral minoxidil and 1 mg dutasteride than with finasteride and topical minoxidil, calling topical minoxidil a scam. Replies varied, with some defending topical minoxidil, questioning the user's application method, and suggesting that previous treatments might be contributing to the observed results.

      community Minoxidil Finasteride heart problems

      in Update  97 upvotes 1 year ago
      A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.

      community Minoxidil hairs not growing to full length

      in Minoxidil  22 upvotes 2 weeks ago
      New hair growth from minoxidil and finasteride is not reaching full length, possibly due to slow growth cycles. Users discuss dosing strategies for oral minoxidil to improve efficacy and minimize side effects, with advice against consuming topical minoxidil orally.

      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  65 upvotes 4 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.

      community Low-Dose Oral Minoxidil Does Not Significantly Affect BP

      in Minoxidil  178 upvotes 6 months ago
      Low-dose oral minoxidil is used for hair loss and does not significantly affect blood pressure but may increase heart rate and cause hypotensive symptoms. Some users experience side effects like palpitations and shortness of breath, while others find it effective; topical minoxidil with tretinoin is also considered.

    Related Research

    1 / 1 results