Minoxidil Overdose: Severe Hypotension and Tachycardia After Ingestion

April 1993 in “ Chest ”

Andrew M. MacMillan, F.J. Warshawski, Richard Steinberg

minoxidil topical minoxidil solution hypotension tachycardia crystalloid solution dopamine phenylephrine male pattern baldness Rogaine

TLDR Man drank minoxidil, caused low blood pressure and fast heartbeat, treatment helped but led to heart damage.

A man ingested 60 ml of 2 percent topical minoxidil solution, resulting in severe hypotension and tachycardia. He was treated with intravenously administered crystalloid solution, dopamine, and phenylephrine infusion, resulting in a partial hemodynamic improvement and resolution of hypotension. The patient suffered a non-Q-wave myocardial infarction as a result of the ingestion. Minoxidil is originally used as an antihypertensive agent and is now approved for the treatment of male pattern baldness. The toxicity of this increasingly common preparation is profound.

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research Minoxidil Overdose: Severe Hypotension and Tachycardia After Ingestion

11 citations, April 1993 in “Chest”

Man drank minoxidil, caused low blood pressure and fast heartbeat, treatment helped but led to heart damage.