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    GlossaryClinical Presentation (Clinical Signs)

    collection of signs and symptoms observed in a patient

    Clinical presentation refers to the collection of signs and symptoms that a patient exhibits, which are used by healthcare professionals to diagnose a condition. For example, in the context of alopecia, the clinical presentation might include noticeable hair thinning, bald patches, or complete hair loss, along with any associated symptoms like itching or inflammation. This term helps both laypeople and professionals understand the observable and reported aspects of a medical condition.

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      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn Verteporfin

      chemical that might completely regrow follicles from hair transplant extractions
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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

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      community Warning: Minoxidil usage around pets

      in Minoxidil  454 upvotes 2 weeks ago
      Minoxidil is highly toxic to pets, especially cats and dogs, even in small amounts. Many users have switched to oral minoxidil to prevent accidental exposure to their pets.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.
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      community Verteporfin and Microneedling

      in Treatments 7 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.