Deslorelin for the Treatment of Hair Cycle Arrest in Intact Male Dogs

    July 2014 in “ Veterinary dermatology
    F Albanese, Eleonora Malerba, Francesca Abramo, Vincenzo Miragliotta, Federico Fracassi
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    TLDR Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.
    In a study evaluating the efficacy of a 4.7 mg deslorelin implant for treating hair cycle arrest (alopecia X) in dogs, 20 dogs with confirmed alopecia X were treated, including 16 intact males and 4 neutered females from various breeds. The results showed that 12 of the 16 intact male dogs (75%) experienced hair regrowth within 3 months, while no hair regrowth was observed in the neutered female dogs. The overall response rate to the treatment was 60%, with no adverse effects reported. The study concluded that deslorelin may be a viable treatment option for intact male dogs suffering from idiopathic hair cycle arrest and presents an alternative to current therapies and castration.
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