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    Glossary Mitotane

    Mitotane is a medication primarily used in the treatment of adrenocortical carcinoma, a rare type of cancer affecting the adrenal glands. Its relevance to hair loss lies in its potential side effects, which can include alopecia or thinning hair due to its impact on adrenal hormone production. Mitotane works by inhibiting steroidogenesis, leading to decreased levels of cortisol and other adrenal hormones, which can disrupt normal hair growth cycles. Key distinguishing characteristics of mitotane include its specific use in cancer therapy and its mechanism of action that targets adrenal function rather than directly affecting hair follicles.

    Research 10 of 60

    1. Adrenal steroid hormone concentrations in dogs with hair cycle arrest (Alopecia X) before and during treatment with melatonin and mitotane Veterinary dermatology · 2004 · 52 citations
    2. Effects of mitotane treatment on human steroid metabolism: implications for patient management Endocrine Connections · 2012 · 26 citations
    3. Growth hormone-responsive alopecia in dogs Journal of the American Veterinary Medical Association · 2005 · 21 citations
    4. Androgen- and Estrogen-Secreting Adrenal Cancers Seminars in Oncology · 2010 · 14 citations
    5. Tertiary hypothyroidism in a dog Irish Veterinary Journal · 2007 · 14 citations
    6. Concurrent hyperadrenocorticism in a minature schnauzer with severe <i>Trichophyton mentagrophytes</i> infection Veterinary Dermatology · 2002 · 5 citations
    7. Modern Approaches to Treatment of Alopecia X in Dogs: Review of Research Russian Journal of Veterinary Pathology · 2023
    8. ODP021 A Feminizing Adrenocortical Carcinoma Presenting with Marie-Antoinette Syndrome Journal of the Endocrine Society · 2022
    9. MON-323 Metastatic Adrenocortical Carcinoma Presenting with Mixed Cushing's and Virilization Syndrome along with Bilateral Pulmonary Emboli Journal of the Endocrine Society · 2019
    10. Pituitary-dependent hyperadrenocorticism in a terrier dog: A case report Journal of Coastal Life Medicine · 2016
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