Hormonal Therapies in Cosmetic Dermatology: Mechanisms, Clinical Applications, and Future Perspectives

    September 2025 in “ Cosmetics
    François Rosset, Marta Marino, Luca Mastorino … Pietro Quaglino
    Studysummary This narrative review synthesized current research on hormonal therapies in cosmetic dermatology, finding they offer promising, evidence-based applications for conditions like aging skin, acne, and melasma, but noting that safety and personalized treatment approaches are essential for responsible clinical use.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 31

    1. Frontiers in the Physiology of Male Pattern Androgenetic Alopecia: Beyond the Androgen Horizon Physiological Reviews · 2025
    2. Extracellular Vesicle as Therapeutic Agents in Anti-Aging: Mechanistic Insights and Future Potential Journal of Controlled Release · 2025
    3. Anti-Androgen Therapy for the Treatment of Female Pattern Hair Loss: A Clinical Review of Current and Emerging Therapies Journal of the American Academy of Dermatology · 2025
    4. Endocrine Controls of Skin Aging Endocrine Reviews · 2025
    5. Efficacy And Safety Of Dutasteride In The Treatment Of Alopecia: A Comprehensive Review Expert Opinion on Pharmacotherapy · 2025
    6. Hormonal Interventions in Skin Wounds: A Mini Review Molecular Medicine · 2024
    7. Guidelines of Care for the Management of Acne Vulgaris Journal of the American Academy of Dermatology · 2024
    8. Dermatologic Manifestations of Thyroid Disease: A Literature Review Frontiers in Endocrinology · 2023
    9. Androgenetic Alopecia: Therapy Update Drugs · 2023
    10. Evaluating the Efficacy of Platelet Rich Plasma and 1550 nm Fractional Laser in Combination and Alone for the Management of Androgenetic Alopecia Journal of Drugs in Dermatology · 2022
    11. What's New in Therapy for Male Androgenetic Alopecia? American Journal of Clinical Dermatology · 2022
    12. The Role of Hormone Therapy in Female Aesthetic Rejuvenation Journal of drugs in dermatology · 2022
    13. Skin, Hair, and Beyond: The Impact of Menopause Climacteric · 2022
    14. Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways Frontiers in Medicine · 2022
    15. Efficacy and Safety of Topical Finasteride Spray Solution for Male Androgenetic Alopecia: A Phase III, Randomized, Controlled Clinical Trial Journal of The European Academy of Dermatology and Venereology · 2021
    16. Thyroid Hormone Action in Epidermal Development and Homeostasis and Its Implications in the Pathophysiology of the Skin Journal of endocrinological investigation · 2021
    17. Hormonal Contraceptives And Dermatology American Journal of Clinical Dermatology · 2020
    18. Topical L-Thyroxine: The Cinderella Among Hormones Waiting to Dance on the Floor of Dermatological Therapy? Experimental Dermatology · 2020
    19. A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia Expert Opinion on Biological Therapy · 2020
    20. Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris American Journal of Clinical Dermatology · 2019
    21. Androgens in Women: Hormone-Modulating Therapies for Androgen-Mediated Cutaneous Disorders Journal of The American Academy of Dermatology · 2018
    22. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis Journal of The European Academy of Dermatology and Venereology · 2018
    23. Sex Hormones and Acne: The Role of the Skin as an Endocrine Organ Clinics in dermatology · 2016
    24. Collagen and Fractionated Platelet-Rich Plasma Scaffold for Dermal Regeneration Plastic and reconstructive surgery/PSEF CD journals · 2016
    25. Skin Connective Tissue and Aging Best Practice & Research in Clinical Obstetrics & Gynaecology · 2013
    26. Effect of Estrogens on Skin Aging and the Potential Role of SERMs Clinical Interventions in Aging · 2007
    27. Sexual Hormones in Human Skin Hormone and metabolic research · 2007
    28. Effect of Estrogens on Skin Aging and the Potential Role of Selective Estrogen Receptor Modulators Climacteric · 2007
    29. Estrogen Functions in Skin and Skin Appendages Expert Opinion on Therapeutic Targets · 2005
    30. Localization of Sex Steroid Receptors in Human Skin PubMed · 2004
    31. Skin Aging and Menopause: Implications for Treatment American Journal of Clinical Dermatology · 2003