Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways

July 2023 in “ International journal of molecular sciences ”

D. H. Ahn, Hyungjun Kim, Bombi Lee, Dae‐Hyun Hahm

alopecia areata autoimmune pathway apoptotic pathway substance P corticotropin-releasing hormone hair follicle inflammation CD8+ T cells p75NTR TrkA JAK-STAT inhibitors AA SP CRH HF JAK inhibitors

Studysummary This review discusses the association between emotional stress-related neuropeptides and the pathogenesis of alopecia areata, reporting no new experimental findings.

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Systematic Review of Newer Agents for the Management of Alopecia Areata in Adults: Janus Kinase Inhibitors, Biologics and Phosphodiesterase-4 Inhibitors

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This review discusses the role of the immune niche in hair follicle regeneration and its impact on different forms of alopecia, highlighting research gaps and potential therapeutic strategies.

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